INTRODUCTION
VENDEP D 100MG contains Desvenlafaxine which belongs to the group of medicines called Antidepressants. It is used in adults to treat the major depressive disorder. Major depressive disorder (also known as clinical depression) is a mental health disorder characterized by persistent depressed mood, lack of interest, feeling of guilt, sleep disturbances or suicidal thoughts for a prolonged period (more than 2 weeks) that causes significant impairment in performing day-to-day activities.
Take VENDEP D 100MG for the stipulated duration mentioned by your doctor. Although you might feel improvement in your condition after 2 weeks of therapy with VENDEP D 100MG, it may take several weeks for VENDEP D 100MG to deliver complete benefits. Therefore, continue to take VENDEP D 100MG for the stipulated duration recommended by your doctor even if you feel better during the midway of the therapy.
Before taking VENDEP D 100MG, inform your doctor if you have high-fat levels in your blood or any liver, kidney or heart problems. You must also inform your doctor if you have or have a family history of bipolar disorder, mania or epilepsy. Do not take VENDEP D 100MG if you are pregnant or breastfeeding without consulting your doctor.
Talk to your doctor if you are currently taking other antidepressant medicines (such as monoamine oxidase inhibitors (Ex. isocarboxazid, phenelzine and tranylcypromine)) while taking VENDEP D 100MG. You must also inform your doctor if you have taken any antidepressant (especially monoamine oxidase inhibitor) within the last 14 days VENDEP D 100MG may make you feel dizzy or sleepy. Therefore, do not drive or operate any heavy tools or machines that require complete concentration.
Other side effects might include decreased sex drive, increased sweating, constipation and dry mouth. Consult your doctor if any of these side effects worsen. Also, inform your doctor immediately if you experience worsening of depression, unusual behaviour or suicidal thoughts after taking VENDEP D 100MG.
USES OF VENDEP D 100MG
Treats major depressive disorder (depression) in adults
HOW VENDEP D 100MG WORKS
VENDEP D 100MG is a potent antidepressant drug. It contains a medicine called desvenlafaxine which is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It acts by increasing the levels of certain chemicals (serotonin and norepinephrine) within the brain that elevates your mood and stabilizes mental health. As a result, it makes you feel active and energetic.
DIRECTIONS FOR USE
Take VENDEP D 100MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. VENDEP D 100MG can be taken with or without food. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Continue to take VENDEP D 100MG for the stipulated duration recommended by your doctor even if you feel better during the midway of the therapy.
SIDE EFFECTS OF VENDEP D 100MG
COMMON
Nausea
Dizziness, tiredness
Feeling sleepy or having difficulty sleeping
Increased sweating
Constipation, decreased appetite, dry mouth, diarrhoea
Anxiety
Decreased sex drive, delayed ejaculation, problems in erection
Feeling shaky
Difficulty in passing urine
Weight gain or weight loss
Stop taking VENDEP D 100MG and contact your doctor immediately if you experience any of the following side effects:
Signs of serotonin syndrome (feeling agitated, hallucinations, confusion, loss of consciousness, fast heartbeat, feeling dizzy, increased sweating, flushing, tremors, stiff muscles, or muscle twitching, loss of coordination, nausea, vomiting, diarrhoea, or seizures)
Worsening of hypertension (high blood pressure)
Increased signs of bleeding or bruising
Problems in vision (such as blurred vision, eye swelling or pain, seeing halos around lights and glaucoma)
Fits (seizures)
Low blood sodium levels (causing headache, nausea, difficulty in concentration, memory impairment, confusion, feeling weak or unsteady, hallucinations, fainting or seizures)
Troubled breathing, chest pain or coughing
Worsening of depression, suicidal thoughts or behaviour
Behavioural changes (such as anxiety, panic attacks, difficulty in sleeping, irritability, restlessness)
Severe upper abdominal pain, swollen and tender abdomen, fever
HOW TO MANAGE SIDE EFFECTS
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.
Constipation:
Eat plenty of fibre-rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Nausea:
Take VENDEP D 100MG with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Consult your doctor if your nausea worsens.
WARNING & PRECAUTIONS
PREGNANCY
VENDEP D 100MG is generally not recommended for use in pregnant women. If you become pregnant while undergoing therapy with VENDEP D 100MG, inform your doctor immediately.
BREASTFEEDING
VENDEP D 100MG is generally not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking VENDEP D 100MG.
ALCOHOL
Avoid consumption of alcohol while taking VENDEP D 100MG.
KIDNEY
VENDEP D 100MG should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
LIVER
VENDEP D 100MG should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take VENDEP D 100MG if you are allergic to Desvenlafaxine or Venlafaxine.
HEART DISEASE
VENDEP D 100MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.
OTHERS
Before taking VENDEP D 100MG, inform your doctor if you:
Have had stroke or any other circulatory disorders
Have or ever had any bleeding problems
Have or have a family history of various mental illness (such as bipolar disorder, mania and hypomania)
Have high blood cholesterols levels
Have ever felt extremely sad with suicidal thoughts or behaviour
Have or ever had seizures (fits)
Have low blood sodium levels (causing tiredness, confusion and muscle weakness)
Have glaucoma
Use in pediatrics:
VENDEP D 100MG is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before administration.
Use in geriatrics:
VENDEP D 100MG should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions –
Before taking VENDEP D 100MG, inform your doctor if you are taking any of the following medicines such as:
Other medicines used to treat depression such as monoamine oxidase inhibitors (Ex. moclobemide, isocarboxazid, phenelzine and tranylcypromine), tricyclic antidepressants (Ex. amitriptyline, nortriptyline), lithium, fluoxetine, sertraline, citalopram, escitalopram etc.
Linezolid (an antibiotic used to treat bacterial infection)
Intravenous methylene blue (used to treat abnormal methemoglobin levels in the blood)
Medicines used to treat migraine headaches (such as sumatriptan, zolmitriptan)
Fentanyl (an opioid analgesic used for pain relief)
Tramadol (used for pain relief)
Tryptophan (an amino acid used for maintaining mental health)
Buspirone (a medicine used to reduce anxiety)
Amphetamines (used as CNS stimulants) Ex. dexamphetamine and lisdexamphetamine
Dextromethorphan (a cough medicine)
Methadone (a medicine used to treat pain or drug addiction)
Pentazocaine (an anaesthetic used to cause numbness before surgeries)
St. John’s Wort (a herbal medicine used to treat depression)
Medicines that can affect blood clotting (such as aspirin or warfarin)
Non-steroidal anti-inflammatory drugs (used for pain relief) Ex. paracetamol, ibuprofen, diclofenac
Medicines used to treat mood and anxiety (such as barbiturates (Ex. phenobarbital), benzodiazepines (Ex. diazepam, clonazepam, alprazolam))
Medicines used to treat psychotic disorders (Ex. chlorpromazine, prochlorperazine, trihexiphenidyl)
Overdosage:
If you or anyone else accidentally consumed more VENDEP D 100MG, consult your doctor immediately or visit the nearby hospital. Symptoms of an overdose might include headache, nausea, vomiting, dizziness, feeling agitated, constipation, diarrhoea, dry mouth, numbness of body parts and fast heart rate.
SYNOPSIS
Drug : Desvenlafaxine
Pharmacological Category : Selective Serotonin and Norepinephrine Reuptake Inhibitor (SNRI)
Therapeutic Indication : Major depressive disorder
Dosage Forms : Tablet
FAQs ABOUT VENDEP D 100MG
What is the use of VENDEP D 100MG?
VENDEP D 100MG is an antidepressant medicine used to treat depression in adults.
How long does it take for VENDEP D 100MG to work?
It may take several weeks for VENDEP D 100MG to heal your condition. Therefore, continue to take VENDEP D 100MG for the stipulated duration recommended by your doctor without any interruption.
Is VENDEP D 100MG a strong antidepressant?
Yes. VENDEP D 100MG is a strong antidepressant that effectively controls signs of depression. It works by increasing the levels of certain chemicals (serotonin and norephedrine) within the brain that stabilizes mental health.
What is the best time to take VENDEP D 100MG?
Take VENDEP D 100MG approximately at the same time each day. You can take VENDEP D 100MG either in the morning or in the evening as per the doctor’s instructions. Taking it at the same time each day will have the best effect and it would also help you remember your daily dose.
What is the difference between Venlafaxine and Desvenlafaxine?
Both Venlafaxine and Desvenlafaxine are selective serotonin and norepinephrine reuptake inhibitor (SSNRI) used to treat depression. Desvenlafaxine is the primary active metabolite of venlafaxine. Following administration, it reaches the site of action with limited bioconversions. Whereas venlafaxine following administration must get converted into desvenlafaxine before providing necessary effects.
Can VENDEP D 100MG be used to reduce anxiety?
VENDEP D 100MG is a prescription medicine used to treat depression. It has been shown to reduce anxiety. However, there is no proper evidence to prove that. If you wish to control anxiety using VENDEP D 100MG, speak with your doctor for advice.
How do VENDEP D 100MG works?
VENDEP D 100MG is a potent antidepressant drug. It acts by increasing the levels of certain chemicals (serotonin and norepinephrine) within the brain that elevates your mood and stabilizes mental health. As a result, it makes you feel active and energetic.
Can I take VENDEP D 100MG in the mornings?
Take VENDEP D 100MG approximately at the same time each day. You can take VENDEP D 100MG either in the morning or in the evening as per the doctor’s instructions. Taking it at the same time each day will have the best effect and it would also help you remember your daily dose.
Can VENDEP D 100MG cause weight gain?
Yes. Weight gain is one of the common side effects of taking VENDEP D 100MG. If this side effect bothers you, contact your doctor.
Will VENDEP D 100MG reduce my sex drive?
Yes. VENDEP D 100MG may affect your sexual life. It may decrease sex drive or cause problems in orgasm, ejaculation or erection. Therefore, consult your doctor if you experience any such symptoms.
Will the use of VENDEP D 100MG make you feel sleepy or tired?
Yes, VENDEP D 100MG can make you feel sleepy, drowsy, or tired. Do not drive or handle heavy machines or tools if you feel drowsy or sleepy. Avoid consumption of alcohol as it can aggravate your drowsiness.
What precautions must be followed while taking VENDEP D 100MG?
Before taking VENDEP D 100MG, inform your doctor if you have high blood fat levels or any liver, kidney or heart problems. You must also inform your doctor if you have or have a family history of bipolar disorder, mania or epilepsy. Do not take VENDEP D 100MG if you are pregnant or breastfeeding without consulting your doctor. Avoid taking other antidepressant medicines concomitantly while taking VENDEP D 100MG without consulting your doctor. Take VENDEP D 100MG for the stipulated duration recommended by your doctor to achieve better results. Contact your doctor immediately if you experience worsening of depression, unusual behaviour or suicidal thoughts after taking VENDEP D 100MG.
Can VENDEP D 100MG be used in children?
VENDEP D 100MG is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before administration.
What to do if I forget to take a dose of VENDEP D 100MG?
If you forget to take a dose of VENDEP D 100MG, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of VENDEP D 100MG to compensate for a missed dose, as it could lead to toxicity.
Will taking a higher dose of VENDEP D 100MG than the prescribed one be beneficial?
No, taking a higher dose of VENDEP D 100MG will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Can I stop taking VENDEP D 100MG once my symptoms subside?
No. Do not stop taking VENDEP D 100MG without consulting your doctor even if you feel better during the mid-way of the therapy. You may feel better after 2 weeks of therapy with VENDEP D 100MG, but it might take several weeks for you to experience complete benefits. Also, sudden discontinuation of therapy may cause withdrawal symptoms such as headache, dizziness, nausea, irritability, lack of sleep, diarrhoea, anxiety, abnormal dreams, fatigue and increased sweating.
Can VENDEP D 100MG be taken daily?
Yes. VENDEP D 100MG can be taken daily as per your doctor’s instruction. However, if you are doubtful, consult your doctor.
REFERENCES
1. Barbara G Wells, Joseph T. DiPiro, Terry L. Schwinghammer and Cecily V. DiPiro. Major Depressive Disorder. Pharmacotherapy Handbook. Nineth Edition. Page – 715 & 718.
2. Harrison’s Manual of Medicine. Psychiatric Medication. 18th Edition. Page – 1327.
3. Raheel Naseeruddin, Alan Rosani and Raman Marwaha. Desvenlafaxine. NIH. National Library of Medicine. National Center of Biotechnology Information. StatPearls. [Revised in July 2022]. [Accessed on 30th August 2022] https://www.ncbi.nlm.nih.gov/books/NBK534829/#:~:text=Desvenlafaxine%20is%20an%20antidepressant%20that,treat%20hot%20flashes%20during%20menopause
4. Michael R. Liebowitz and Karen A. Tourian. Efficacy, Safety and Tolerability of Desvenlafaxine 50 mg/d for the Treatment of Major Depressive Disorder: A Systematic Review of Clinical Trials. NIH. National Library of Medicine. National Center of Biotechnology Information. PMC PubMed Central. 2010. [Accessed on 30th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947544/
5. Pfizer Ltd. U.S. Food & Drug Administration. [Revised in July 2011] [Accessed on 30th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021992s030lbl.pdf
6. Pfizer Ltd. MEDICATION GUIDE PRISTIQ® (pris-TEEK) (desvenlafaxine) extended-release tablets. [Revised in January 2022] [Accessed on 30th August 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=14010
7. Pfizer Ltd. PACKAGE INSERT PRISTIQ® (desvenlafaxine) Extended-Release Tablets. [Revised in September 2021] [Accessed on 30th August 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=12155
8. Pfizer Australia Pty Ltd. PRISTIQ®. Healthlinks.Net.AU. [Revised in March 2022] [Accessed on 30th August 2022] http://secure.healthlinks.net.au/content/pf/retriever.cfm?product=pfcprist11212
PRODUCT DETAILS
Net Qty
1 N
Item Weight
17.5 g
Ingredient
DESVENLAFAXINE 100MG
Hsn Code
30049099
Show more
Reviews
There are no reviews yet.