INTRODUCTION
PBREN 50MG contains Pregabalin which belongs to a group of medicines known as anticonvulsants. It is used to treat epilepsy, neuropathic pain and generalized anxiety disorder (GAD). Epilepsy is a disorder in which nerve cell activity in brain is disturbed, causing seizures. This medicine is used to treat the certain form of epilepsy (partial seizures with or without secondary generalization) in adults. Damage to nerves outside of the brain and spinal cord leads to peripheral and central neuropathic pain. This medicine is used to treat pain caused by damaged nerves. Neuropathic pain may have an impact on physical and social functioning and overall quality of life associated with the mood changes, disturbances in sleep and fatigue.
Generalized Anxiety Disorder (GAD) is characterized by the persistent and excessive worry about a number of different things. PBREN 50MG efficiently helps in reducing the psychological symptoms of this disorder. Always take PBREN 50MG exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. Do not drive or operate any machinery while taking this medicine, it may make you feel drowsy. This medicine is not recommended for children and adolescents below 18 years of age, pregnant or breastfeeding. Before taking, tell your doctor if you have liver, kidney or heart problems. The common side effects are dizziness, drowsiness, headache and diarrhea.
USES OF PBREN 50MG
Treat epilepsy, neuropathic pain and Generalized Anxiety Disorder (GAD) in adults
HOW PBREN 50MG WORKS
Pregabalin works by reducing abnormal electrical activity in the brain and stops seizures. In neuropathic pain, it interferes with pain messages travelling through the brain and down the spine and blocks the pain.
DIRECTIONS FOR USE
Always take PBREN 50MG exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water.
SIDE EFFECTS OF PBREN 50MG
SERIOUS
Muscle problems, muscle pain, soreness or weakness
Blurred vision, double vision
Weight gain
COMMON
Dizziness, drowsiness, headache
Increased appetite
Confusion
Decrease in sexual libido
Memory impairment
Difficulty in speaking
Tingling feeling, numbness
Fatigue
Vertigo
Dry mouth, constipation
Vomiting, nausea
Flatulence, diarrhea
Swelling of the body including extremities
Feeling drunk, abnormal style of walking
Weight gain
Muscle cramp, joint pain, back pain
Sore throat
RARE
Liver failure, inflammation of the liver
Inflammation of the pancreas
Difficulty in swallowing
Slow or reduced movement of the body
Increased fluid in the abdomen or lungs
Convulsions
Heart rhythm disturbances
Muscle damage
HOW TO MANAGE SIDE EFFECTS
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Diarrhea:
Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicines without consulting your doctor.
WARNING & PRECAUTIONS
PREGNANCY
PBREN 50MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.
BREASTFEEDING
PBREN 50MG should be used with caution for breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machinery while taking this medicine, it may make you feel drowsy.
ALCOHOL
Avoid consumption of alcohol while taking this medicine.
KIDNEY
PBREN 50MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
PBREN 50MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take if you are allergic to the medicine.
LUNGS
PBREN 50MG should be taken with caution in patients with lung disease. Consult your doctor for advice.
INTERACTIONS
Talk to your doctor if you are taking:
Other medicines which have or had sedative effects (including opioids)
Oxycodone (used as a painkiller)
Lorazepam (used for treating anxiety)
SYNOPSIS
Drug : Pregabalin
Pharmacological Category : Anticonvulsants
Therapeutic Indication :
Epilepsy, Neuropathic pain and Generalized anxiety disorder (GAD) in adults
Dosage Forms : Tablet, Capsule, Injection
MORE INFORMATION
Store at room temperature 15-25°C and keep out of reach of children.
FAQs ABOUT PBREN 50MG
Can PBREN 50MG be used in pregnant women?
No. It is not recommended for use in the pregnant women. Consult your doctor before taking this medicine.
How does PBREN 50MG work for pain?
It works by changing the way that nerves send messages to your brain. If the messages are reduced, then pain will be reduced.
REFERENCES
1. Goodman and Gilman’s: The Pharmacological Basis of Therapeutics. Chapter – 21 – Pharmacotherapy of the epilepsies; 12th ed. New York, New York: McGraw-Hill Medical, 2011. Page – 599.
2. Charles P Taylor, Timothy Angelotti, Eric Fauman; Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery; [Published on 2007] https://pubmed.ncbi.nlm.nih.gov/17126531/
3. Parke-Davis Div of Pfizer Inc; U.S. Food & Drug Administration; [Revised on 06/2020] [Accessed 19 Oct 2020] http://labeling.pfizer.com/ShowLabeling.aspx?id=9678
4. Accord Healthcare Limited; Electronic Medicines Compendium (EMC); [Revised on 07/2020] [Accessed 19 Oct 2020] https://www.medicines.org.uk/emc/files/pil.7448.pdf
5. Pfizer Pharmaceuticals LLC; Parke-Davis Div of Pfizer Inc;U.S. Food & Drug Administration; [Revised on 06/2011] [Accessed 19 Oct 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021446s026,022488s005lbl.pdf
VIDEOS
Pregabalin CAPSULE – Drug Information
Pregabalin CAPSULE : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage
Net Qty
1 N
Item Weight
17.5 g
Ingredient
PREGABALIN 50MG
Hsn Code
30049082
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