Mamofen 10mg Tablet 10’S

INTRODUCTION

MAMOFEN 10MG TABLET contain Tamoxifen which belongs to the group of medicines called Anti-estrogens. It is used to treat breast cancer. This medicine is also used to treat infertility in women caused by a failure to produce and release eggs and reduce the risk of developing breast cancer.

Breast cancer is a disease in which cells in the breast grow out of control. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer.

Along with this treatment, your doctor might ask you to make certain lifestyle changes such as eating a healthy diet, healthy sleep habits and managing your weight. Prior to the treatment, your doctor may want you to take certain breast examinations to understand your existing condition.

MAMOFEN 10MG TABLET is not recommended for use in patients with a history of blood clots (including family), taking treatment for infertility.

MAMOFEN 10MG TABLET should be used with caution in patients with a history of hereditary angioedema.

MAMOFEN 10MG TABLET is not recommended for use in pregnant women. Inform your doctor before taking MAMOFEN 10MG TABLET if you are breastfeeding.

MAMOFEN 10MG TABLET is not recommended for use in children. The most common side effects of taking MAMOFEN 10MG TABLET are nausea, fluid retention, skin rash, hot flushes, tiredness and anemia. Consult your doctor if any of the above side effects worsen or persist for a long time.

USES OF MAMOFEN 10MG TABLET
Used to treat breast cancer
HOW MAMOFEN 10MG TABLET WORKS

MAMOFEN 10MG TABLET works by binding to estrogen receptors and blocking the effects of estrogen (natural female hormone) in the breast tissue. This slows down the growth and multiplication of breast cancer cells.

DIRECTIONS FOR USE

Take MAMOFEN 10MG TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF MAMOFEN 10MG TABLET
COMMON
Nausea, vomiting
Fluid retention
Skin rash
Hot flushes (feeling of warmth)
Tiredness
Anemia
Changes in vision due to cataracts or changes to the retina of eye
Increased amounts of fats in your blood
Allergic reactions
Leg cramps
Changes in the womb (including changes to its lining and benign growths)
Headache, light-headedness
Itching of the genitals
Thinning of the hair
Diarrhea
Constipation
Changes in blood tests of liver function
Formation of fatty liver cells
Muscle pain
Sensory changes
Increased risk of blood clots
UNCOMMON
Blood problems
Changes in vision and difficulty seeing
Swelling of the pancreas
Changes in the amount of calcium in your blood
Inflammation of the lungs
RARE
Changes in the cornea of eye
Problems with the nerve that connects retina to your brain
Swelling of the optic nerve
Damage to blood vessels causing reddish or purplish dots on the skin
Severe skin disorder (redness, blistering and peeling)
Non-cancerous mass in inner lining of vagina
Worsening of the symptoms of breast cancer such as an increase in pain and/or an increase in the size of the affected tissue may occur

Stop taking MAMOFEN 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:

Swelling of the calf or leg, chest pain, being short of breath or suddenly feeling weak
Symptoms of a stroke (sudden onset of weakness or paralysis of the arms or legs, being unable to move the arms or legs, sudden difficulty with speaking, walking, in holding things or in thinking)
Difficulty in breathing, swelling of the face, lips, tongue or throat which may make it difficult to swallow (angioedema)
Nettle rash (hives or urticaria)
Reddish non-elevated, target-like or circular patches on the trunk, often with central blisters, skin peeling, ulcers of mouth, throat, nose, genitals and eyes (Stevens-Johnson syndrome, toxic epidermal necrolysis)
Unusual bleeding from vagina
Irregular periods, especially if associated with heavier bleeding as this could be a warning sign for a certain type of cancer affecting the lining of womb (endometrial cancer)
Vaginal discharge
Feeling of discomfort in the lower tummy (pelvis)
HOW TO MANAGE SIDE EFFECTS

Nausea or Vomiting:

Take this medicine with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of water or fruit juice to keep hydrated. Do not consume any medicine on your own without consulting your doctor.

Headache:

Avoid bright lights, taken enough rest and drink lots of water.

WARNING & PRECAUTIONS
PREGNANCY

MAMOFEN 10MG TABLET is not recommended for use in pregnant women. Consult your doctor immediately if you think you may have become pregnant after starting the treatment.

BREASTFEEDING

Inform your doctor if you are breastfeeding before taking MAMOFEN 10MG TABLET.

DRIVING AND USING MACHINES

Do not drive or handle any machines if you experience tiredness after taking MAMOFEN 10MG TABLET.

ALLERGY

Do not take MAMOFEN 10MG TABLET if you are allergic to Tamoxifen or any other ingredients of this medicine.

OTHERS

MAMOFEN 10MG TABLET is not recommended for use if you:

Are taking treatment for infertility
Have or had blood clots in the past  
Have family history of blood clots
Have illness which runs in the family that increases the risk of blood clots

Before taking MAMOFEN 10MG TABLET, inform your doctor if you:

Are to undergo planned surgery
Have a history of hereditary angioedema
Are intolerant to certain sugars (lactose)

Use in Pediatrics:

MAMOFEN 10MG TABLET is not recommended for use in children. Consult your doctor before taking.

INTERACTIONS

A. Drug – Drug interactions:

Before taking MAMOFEN 10MG TABLET, inform your doctor if you are taking any of the following medicine:

Oral contraceptives
Hormone replacement therapy (HRT)
Antidepressants (Ex. paroxetine, fluoxetine)
Bupropion (used as antidepressant or aid smoking cessation)
Quinidine (used to treat cardiac arrhythmia)
Cincalet/cinacalcet (used to treat disorders of the parathyroid gland)
Blood thinning medicines such as warfarin 
Rifampicin (used for tuberculosis)
Medicines used to treat breast cancer (Ex. anastrozole, letrozole and exemestane)

Overdosage:

If you or anyone else accidentally takes too much of MAMOFEN 10MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are uncontrollable shaking of a part of the body, unsteadiness and dizziness.

SYNOPSIS
Drug :   Tamoxifen
Pharmacological Category :   Anti-estrogens
Therapeutic Indication :   Breast cancer
Dosage Forms :   Tablet, Capsule
MORE INFORMATION
Keep MAMOFEN 10MG TABLET out of reach of children
Do not store above 25°C
FAQs ABOUT MAMOFEN 10MG TABLET

What is MAMOFEN 10MG TABLET used for?

It is used to treat breast cancer. This medicine is also used to treat infertility in women caused by a failure to produce and release eggs and reduce the risk of developing breast cancer.

What if I stop taking MAMOFEN 10MG TABLET?

Do not stop taking MAMOFEN 10MG TABLET, even if you start feeling well, unless your doctor tells you. Stopping it early may increase the risk of breast cancer coming back.

Can MAMOFEN 10MG TABLET be used in pregnant women?

No, MAMOFEN 10MG TABLET is not recommended for use in pregnant women as it can affect the unborn child.

What are common side effects of taking MAMOFEN 10MG TABLET?

MAMOFEN 10MG TABLET can cause hot flushes, night sweats, sleep disturbance, vaginal irritation, headache, loss of sex drive and mood changes, fluid retention, nausea and vomiting.

What if I forget to take MAMOFEN 10MG TABLET?

If you forget to take MAMOFEN 10MG TABLET, take it as soon as you remember. If it is near to your next dose, skip it and follow your usual dosing schedule. Do not take two doses at the same time.

REFERENCES

1. KD Tripathi. Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology. Eighth Edition. 2019. Page –337-340.

2. CP Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on 31st May 2022] https://www.medicines.org.uk/emc/files/pil.2247.pdf

3. Tamoxifen. Mayoclinic. [Revised on April 2022] [Accessed on 31st May 2022] https://www.mayoclinic.org/diseases-conditions/breast-cancer/symptoms-causes/syc-20352470

4. Tamoxifen. Medlineplus. [Revised on January 2018] [Accessed on 31st May 2022] https://medlineplus.gov/druginfo/meds/a682414.html

USEFUL DIAGNOSTIC TESTS
Breast ultrasound
Mammogram
Breast MRI
Biopsy
PRODUCT DETAILS
Net Qty
1 N
Item Weight
17.5 g
Ingredient
TAMOXIFEN CITRATE 10MG
Hsn Code
30049048
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