INTRODUCTION
CITITOP SYRUP contains Citicoline which belongs to a group of medicines called Psychostimulants. CITITOP SYRUP is used in adults to treat disturbances of consciousness that occurs due to head injuries, brain operation and acute cerebral infraction.
CITITOP SYRUP is also used to treat cognitive dysfunction that occurs due to Alzheimer’s disease (brain disease that affects memory and thinking skills) and other cerebrovascular disease. It is also indicated for use in acute and recovery phase of cerebral infarction (condition that occurs due to poor blood supply to the brain) which is also used to treat Parkinson’s disease (age related degenerative brain condition).
CITITOP SYRUP is not recommended for use in patients allergic to Citicoline. It is also not recommended for use in patients suffering from hypertonia (muscle overactivity).
Before taking CITITOP SYRUP, inform your doctor if you are scheduled for any surgery and/or have kidney problems (such as renal insufficiency)/liver problems (such as hepatic insufficiency).
CITITOP SYRUP should be used with caution in pregnant and breastfeeding women only if necessary. It is not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.
The most common side effects of taking CITITOP SYRUP are nausea, vomiting, constipation, headache, low blood pressure and/or agitation. Consult your doctor if any of these symptoms worsens.
USES OF CITITOP SYRUP
Treats disturbances of consciousness that occurs due to head injuries, brain operation and acute cerebral infraction
Treats cognitive dysfunction that occurs due to Alzheimer’s disease and other cerebrovascular disease
Treats Parkinson’s disease
Helps in the acute and recovery phase of cerebral infarction/ischemic stroke in affected individuals
HOW CITITOP SYRUP WORKS
CITITOP SYRUP works by increasing the synthesis of phosphatidylcholine (chemical that produces acetylcholine, responsible for memory and other bodily functions) which leads to improved cerebral function and cognitive function in Alzheimer’s disease and Parkinson’s disease. It also works by repairing neuronal membranes and damaged cholinergic neurons via potentiation of acetylcholine production and reduction of free fatty acid accumulation at stroke-induced nerve damage site which results in the prevention neuronal cell death thus helping in the recovery phase of cerebral infarction in affected individuals.
DIRECTIONS FOR USE
Oral Drops:
Take CITITOP SYRUP as advised by your physician. Shake well before use. Measure it with a dropper and take it as directed. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Syrup & Solution:
Take CITITOP SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF CITITOP SYRUP
COMMON
Nausea, vomiting, constipation
Headache
Agitation
Low blood pressure
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Take CITITOP SYRUP with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.
Constipation:
Try to eat high-fiber foods such as vegetables, cereals, fresh fruit and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.
Headache:
If CITITOP SYRUP causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking CITITOP SYRUP. If it lasts more than a week or severe, inform your doctor.
WARNING & PRECAUTIONS
PREGNANCY
CITITOP SYRUP should be used with caution during pregnancy only if it is clearly necessary. Consult your doctor before taking CITITOP SYRUP.
BREASTFEEDING
CITITOP SYRUP should be used with caution in breastfeeding women only if it is clearly necessary. Consult your doctor before taking CITITOP SYRUP.
KIDNEY
CITITOP SYRUP should be used with caution in patients with kidney problems such as kidney insufficiency. Consult your doctor before taking CITITOP SYRUP.
LIVER
CITITOP SYRUP should be used with caution in patients with liver problems such as liver insufficiency. Consult your doctor before taking CITITOP SYRUP.
ALLERGY
Do not take CITITOP SYRUP if you are allergic to Citicoline or any of the other ingredients of this medicine.
OTHERS
CITITOP SYRUP is not recommended for use if you have:
Are hypertonic (muscle overactivity)
Use in Paediatrics:
CITITOP SYRUP is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking the medicine.
Use in Geriatrics:
CITITOP SYRUP should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.
INTERACTIONS
A.Drug – Drug interactions:
Before taking CITITOP SYRUP, inform your doctor if you are taking any of the following medicine:
Levodopa (medicine used to treat Parkinson’s disease)
Meclofenoxate (used as a dietary supplement to treat dementia)
Overdosage:
If you or anyone else accidentally take too much of CITITOP SYRUP, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
SYNOPSIS
Drug : Citicoline
Pharmacological Category : Pyrimidine ribonucleoside diphosphates
Therapeutic Indication : Disturbance in consciousness (due to head injuries, brain operation, acute cerebral infraction), Cognitive dysfunction (due to Alzheimer’s disease), Parkinson’s disease
Dosage Forms : Tablet, Injection, Syrup, Solution, Oral drops
MORE INFORMATION
Keep CITITOP SYRUP out of reach of children
Do not store CITITOP SYRUP above 30°C
FAQs ABOUT CITITOP SYRUP
What is CITITOP SYRUP is used for?
CITITOP SYRUP is used in adults to treat disturbances of consciousness that occurs due to head injuries, brain operation and acute cerebral infraction. It is also used to treat cognitive dysfunction that occurs due to Alzheimer’s disease (brain disease that affects memory and thinking skills) and other cerebrovascular disease. The medicine is also indicated for use in acute and recovery phase of cerebral infarction (condition that occurs due to poor blood supply to the brain) which is also used to treat Parkinson’s disease (age related degenerative brain condition) in affected individuals.
What are the side effects of CITITOP SYRUP?
The most common side effects of taking CITITOP SYRUP are nausea, vomiting, constipation, headache, low blood pressure and/or agitation. Consult your doctor if any of these symptoms worsens.
How CITITOP SYRUP works?
CITITOP SYRUP works by increasing the synthesis of phosphatidylcholine (chemical that produces acetylcholine, responsible for memory and other bodily functions) which leads to improved cerebral function and cognitive function in Alzheimer’s disease and Parkinson’s disease. It also works by repairing neuronal membranes and damaged cholinergic neurons via potentiation of acetylcholine production and reduction of free fatty acid accumulation at stroke-induced nerve damage site which results in the prevention neuronal cell death thus helping in the recovery phase of cerebral infarction in affected individuals.
What happens if more than required dosage of CITITOP SYRUP is taken?
If you or anyone else accidentally take too much of CITITOP SYRUP, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
Can CITITOP SYRUP be used in pregnant and breastfeeding women?
Yes, CITITOP SYRUP can be used but with caution in pregnant and breastfeeding women only if it is clearly necessary. Consult your doctor before taking CITITOP SYRUP.
REFERENCES
1. KD. Tripathi. CNS Stimulants and Cognition Enhancers. Essentials of medical pharmacology. Seventh edition. 2013. Page – 491.
2. Cochrane Stroke Group, Arturo J Martí-Carvajal, Claudia Valli, Cristina Elena Martí-Amarista, Ivan Solà, Joan Martí-Fàbregas, Xavier Bonfill Cosp. Citicoline for treating people with acute ischemic stroke. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in August 2020] [Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406786/
3. Pawel Grieb. Neuroprotective Properties of Citicoline: Facts, Doubts and Unresolved Issues. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2014] [Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933742/
4. Antonino Maria Cotroneo, Alberto Castagna, Salvatore Putignano, Roberto Lacava, Fausto Fantò, Francesco Monteleone,5 Filomena Rocca, Alba Malara, Pietro Gareri. Effectiveness and safety of citicoline in mild vascular cognitive impairment: the IDEALE study. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2013] [Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569046/
5. UniLab, Inc. Citicoline. [Revised in June 2015] [Accessed on 7th May 2022] https://www.unilab.com.ph/products/cholinerv
6. Alkem Laboratories Limited. Ceham. [Accessed on 7th May 2022] https://www.alkemlabs.com/pdf/adverse/Ceham.pdf
USEFUL DIAGNOSTIC TESTS
Magnetic resonance imaging (MRI)
Dopamine transporter (DAT) scan
PRODUCT DETAILS
Country Of Origin
India
Reviews
There are no reviews yet.