XAPILIS 2.5 Tablet 14’s

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INTRODUCTION

XAPILIS 2.5 TABLET contains Apixaban, which belongs to theroup of medicines called Anticoagulants. It is used in adults to prevent blood clots from forming after hip or knee replacement operations and to prevent blood clots (clusters of blood) in patients with an irregular heartbeat (atrial fibrillation). It also helps in the treatment of blood clots in the legs (deep vein thrombosis) and the veins of the lungs (pulmonary embolism) and the prevention of their recurrence in either the legs or lungs.

GBNKEYWORD] is not recommended in patients who have liver disease, active bleeding, or a disease that can lead to active bleeding, such as an active ulcer or a recent bleed in the brain. If you are pregnant or breastfeeding, consult your doctor before taking XAPILIS 2.5 TABLET.

Patients who have kidney disease should use XAPILIS 2.5 TABLET with caution. XAPILIS 2.5 TABLET is not recommended for children and adolescents (under the age of 18). XAPILIS 2.5 TABLET should be used with caution in elderly patients over the age of 75.

The most common side effects of taking XAPILIS 2.5 TABLET are bleeding (eyes, nose,ums, urine, rectum, stomach, or bowel), bruising or swelling, anaemia, low blood pressure, and a quickened heart rate. If any of these symptoms worsen, contact your doctor immediately.

USES OF XAPILIS 2.5 TABLET
Treats blood clots formed in veins of the legs
Prevents the formation of blood clots in heart patients with irregular heartbeat, formation in veins of legs after a hip or knee replacement and the reoccurrence of blood clots in legs or lungs

 

HOW XAPILIS 2.5 TABLET WORKS

XAPILIS 2.5 TABLET helps to prevent the formation of blood clots by acting on the blood clotting mechanism of the body. It blocks clotting factor Xa which is an essential factor in the clotting mechanism.

DIRECTIONS FOR USE

Take XAPILIS 2.5 TABLET as advised by your physician. Swallow the medicine with alass of water. If you have difficulty swallowing the medicine, talk to your doctor about other ways to take XAPILIS 2.5 TABLET. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF XAPILIS 2.5 TABLET
COMMON
Bleeding affecting (eyes, stomach or bowel, rectum, blood in the urine, nose, andums)
Bruising and swelling
Anaemia which may lead to tiredness or paleness
Low blood pressure (faint or have a quickened heartbeat)
Nausea
UNCOMMON
Bleeding in the brain or spinal column, in the mouth or blood in spit when coughing, into the abdomen, from the vagina
Bright/red blood in the stools
Bleeding occurring after the operation including bruising and swelling
Leaking of blood/liquid from the surgical wound/incision (wound secretion) or injection site
Bleeding from a haemorrhoid
Reduced count of platelets in your blood
Yellowing of the skin and eyes
Skin rash
Itching
Hair loss
RARE
Bleeding in the lungs or your throat, into the space behind the abdominal cavity, into a muscle

Stop taking XAPILIS 2.5 TABLET and contact your doctor immediately if you experience any of the following side effects:

Severe allergic reaction (hypersensitivity) causing swelling of lips, mouth, tongue, and throat
Breathing difficulties
HOW TO MANAGE SIDE EFFECTS

Nausea:

Try and take the medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if your symptomets worse.

WARNING & PRECAUTIONS
PREGNANCY

The effects of XAPILIS 2.5 TABLET on pregnancy and the unborn child are not known. Hence it is not recommended during pregnancy. Consult your doctor before taking it.

BREASTFEEDING

It is not known if XAPILIS 2.5 TABLET passes into human breast milk. Consult your doctor for advice before taking this medicine during breastfeeding.

DRIVING AND USING MACHINES

XAPILIS 2.5 TABLET does not impair the ability to drive or use machines. Consult your doctor.

KIDNEY

XAPILIS 2.5 TABLET should be taken with caution in patients with severe kidney disease or who are on dialysis. Consult your doctor before taking it.

LIVER

XAPILIS 2.5 TABLET is not recommended for use in patients with liver disease such as hepatic coagulopathy which may increase the risk of bleeding. Consult your doctor before taking it.

ALLERGY

Do not take XAPILIS 2.5 TABLET if you are allergic to Apixaban.

HEART DISEASE

XAPILIS 2.5 TABLET should be taken with caution in patients with prosthetic heart valves. Consult your doctor before taking it.

OTHERS

XAPILIS 2.5 TABLET is not recommended for use if you:

Had a tube or an injection in your spinal column (for anesthesia)
Have unstable blood pressure

Before taking XAPILIS 2.5 TABLET, inform your doctor if you:

Have bleeding disorders
Have very high blood pressure
Have antiphospholipid syndrome (a disorder of the immune system that increases the risk of blood clots)
Have to undergo surgery which will cause bleeding
Have lactose intolerance

Use in pediatrics:

XAPILIS 2.5 TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking.

 Use ineriatrics:

XAPILIS 2.5 TABLET should be used with caution in elderly patients (aged above 75 years). Consult your doctor before taking it.

INTERACTIONS

A. Drug–Drug Interactions:

Medicines for fungal infections (Ex. ketoconazole)
Antiviral medicines for HIV / AIDS (Ex. ritonavir)
Other medicines that are used to reduce blood clotting (Ex. enoxaparin)
Anti-inflammatory or pain-relieving medicines (Ex. acetylsalicylic acid, naproxen)
Medicines for high blood pressure or heart problems (Ex. diltiazem)
Selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors (used in the treatment of depression) Ex. escitalopram
Medicines to prevent epilepsy or seizures (Ex. phenytoin)
Herbal supplement used for depression (St John’s Wort)
Medicines used to treat tuberculosis or other infections (Ex. rifampicin)

Overdosage:

If you or anyone else accidentally take too much of XAPILIS 2.5 TABLET, consult your doctor immediately or visit the nearby hospital. Overdose can result in increased bleeding.

SYNOPSIS
Drug :   Apixaban
Pharmacological Category :   Anti-coagulants
Therapeutic Indication :   Prevention of blood clots in atrial fibrillation, Deep vein thrombosis, Pulmonary embolism, Deep vein thrombosis following hip or knee replacement       
Dosage Forms :   Tablet
MORE INFORMATION
Keep XAPILIS 2.5 TABLET out of reach from children
Store below 30°C
FAQs ABOUT XAPILIS 2.5 TABLET

Is XAPILIS 2.5 TABLET a blood thinner?

Yes. [GBKEYWORD] is a blood thinner, also called an anticoagulant. It prevents blood clot formation and makes it easier for the blood to flow through the body. XAPILIS 2.5 TABLET blocks an essential factor of the clotting mechanism called factor Xa, which stops the blood from clotting.

What precautions should I take while taking XAPILIS 2.5 TABLET?

Patients taking XAPILIS 2.5 TABLET should inform their doctor about their pre-existing liver, heart, or kidney disease. As XAPILIS 2.5 TABLET is an anti-coagulant and helps in the prevention of blood clot formation, it is important to tell your doctor about any bleeding disorder or any active condition that can cause a bleed. Consult your doctor before taking it.

What if I forget to take a dose of XAPILIS 2.5 TABLET?

Take the dose as soon as you remember, then take the next dose of XAPILIS 2.5 TABLET at the usual time, and then continue as normal. Consult your doctor once.

Can XAPILIS 2.5 TABLET cause low blood pressure?

Yes. Low blood pressure is a common side effect of XAPILIS 2.5 TABLET. You may experience a faster heartbeat. Consult your doctor if the side effect worsens.

Is XAPILIS 2.5 TABLET safe during pregnancy?

The effects of XAPILIS 2.5 TABLET on pregnancy and the unborn child are not known. Hence, it is not recommended during pregnancy. Consult your doctor before taking it.

Can I suddenly stop taking XAPILIS 2.5 TABLET?

No. You should not stop taking XAPILIS 2.5 TABLET suddenly or alter its dose. Doing so can result in the reoccurrence of blood clots and can lead to serious side effects. Talk to your doctor if you notice any side effects.

REFERENCES

1. Joseph T. DiPiro, Robert L. Talbert, Cardiovascular Diseases, Pharmacotherapy: A Pathophysiologic Approach, Eighth Edition. 2011. Page – 324.

2. Joseph P. Broderick, Jordan B. Bonomo, Brett M. Kissela, Jane C. Khoury, Charles J. Moomaw, Kathleen Alwell, Daniel Woo, Matthew L. Flaherty, Pooja Khatri, Opeolu Adeoye, Simona Ferioli, Dawn O. Kleindorfer. Withdrawal of Antithrombotic Agents and Its Impact on Ischemic Stroke Occurrence. NIH. National Library of Medicine. National Center for Biotechnology Information. PubMed Central. June 2011. [Accessed on 20th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166233/

3. CATALENT ANAGNI S.R.L. Electronic Medicines Compendium (EMC). [Revised in September 2021]. [Accessed on 23rd April 2022] https://www.medicines.org.uk/emc/files/pil.4756.pdf

4. Bristol-Myers Squibb Company, Pfizer Inc. Bristol Myers Squib. [Revised in September 2021]. [Accessed on 20th April 2022] https://packageinserts.bms.com/pi/pi_eliquis.pdf

USEFUL DIAGNOSTIC TESTS
CBC
Echocardiography
Duplex Ultrasound
Chest Xray
PRODUCT DETAILS
Country Of Origin
India

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XAPILIS 2.5 Tablet 14's

US$24.00US$32.00 (-25%)

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