VAST ROLD CAPSULE is a combination of Aspirin, Clopidogrel and Rosuvastatin which belongs to theroup of medicines called Antiplatelets and HMG-CoA reductase inhibitors respectively. VAST ROLD CAPSULE is indicated for the treatment of acute coronary syndrome, myocardial infarction (heart attack), angina (chest pain) or stroke (reduced blood supply to brain leading to brain death) that were caused due to clot or plaque formation in the blood vessels supplying the heart.
Acute coronary syndrome is a heart condition caused by plaque rupture or clot formation in the coronary arteries. Symptoms include heart attack, chest pressure or pain while at rest, shortness of breath and sweating.
Along treatment with VAST ROLD CAPSULE follow a healthy low-fat diet as advised by doctor to achieve better results.
Avoid drinking alcohol during the therapy, as it could increase the risk of bleeding in theastrointestinal tract. VAST ROLD CAPSULE is not recommended for use in patients having severe liver, kidney or heart disease. Consult your doctor before taking this medicine.
VAST ROLD CAPSULE isenerally not recommended for use in pregnant or breastfeeding women and in children (below 18 years). Consult your doctor for an alternative therapy.
The most common side effects of taking VAST ROLD CAPSULE are increased bleeding tendency, nausea, indigestion, diarrhea, stomach pain, constipation, muscle pain, dizziness and headache. Contact your doctor if any of these symptoms worsen.
USES OF VAST ROLD CAPSULE
Treats acute coronary syndrome
Treats myocardial infarction
HOW VAST ROLD CAPSULE WORKS
VAST ROLD CAPSULE effectively improves cardiac function and reduces the risk of heart problems, where clopidogrel acts by inhibiting platelet aggregation in the coronary arteries, aspirin acts by blocking the actions of an enzyme called cyclo-oxygenase 1 which is believed to be responsible for catalyzing the synthesis of platelets and rosuvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase, which is required to catalyze the formation of cholesterol, thus preventing clot or plaque formation in the coronary arteries leading to an uninterrupted supply of oxygen and blood to the heart.
DIRECTIONS FOR USE
Take VAST ROLD CAPSULE as advised by your physician. Swallow VAST ROLD CAPSULE with alass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF VAST ROLD CAPSULE
Increased bleeding or bruising
Indigestion, diarrhea, stomach pain, nausea, constipation
Bleeding in theut
Diabetes (high bloodlucose)
Dizziness and headache
Muscle cramps or pain
Weakness or lack of energy
Epistaxis (bleeding from the nose)
Skin rash, itching or skin reactions
Stomach ulcer, vomiting
Excessiveas in stomach or intestine
Tingling or numbness sensation
Signs of decreased platelet count (easy bleeding or bruising)
Enlarged breasts in men (gynecomastia)
Vertigo (spinning sensation)
Lupus-like disease syndrome (including rash, joint disorders and effects on blood cells)
Intracranial hemorrhage (bleeding in the brain)
Stop taking VAST ROLD CAPSULE and contact your doctor immediately if you experience any of the following side effects:
Severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat and neck, difficulty in breathing or swallowing)
Thrombotic Thrombocytopenic Purpura (a blood disorder that causes blood clots in capillaries throughout the body)
Severe skin disorders with fever (Ex. Lyell’s syndrome, Steven-Johnsons syndrome, erythema nodosum, erythema multiforme)
Symptoms of pancreatitis (such as moderate to severe abdominal pain, nausea, vomiting, fever, rapid heart rate)
Jaundice (yellowing of eyes, skin and urine with fever)
Rhabdomyolysis (muscle rupture)
Unusual bleeding (such as blood in vomit or urine, coughing up blood, black stools, purple spots under the skin)
Flu-like symptoms (fever, cough, sore throat, headache and extreme tiredness)
Breathing difficulties (Ex. bronchospasm, asthma attack)
Hemorrhagic vasculitis (inflammation of the blood vessels with bleeding)
Abnormal heavy or prolonged menstrual periods
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Try to take VAST ROLD CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Try to rest and relax.et enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Eat fiber rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom did not improve on its own.
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.
WARNING & PRECAUTIONS
VAST ROLD CAPSULE is not recommended for use in pregnant women. However, consult your doctor before taking VAST ROLD CAPSULE. Women of child-bearing potential should use suitable contraceptive method to avoid pregnancy while taking VAST ROLD CAPSULE.
VAST ROLD CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking VAST ROLD CAPSULE.
DRIVING AND USING MACHINES
VAST ROLD CAPSULE does not affect your ability to drive or operate machines. However, if you experience dizziness during treatment with VAST ROLD CAPSULE, do not drive or operate any machines. Consult your doctor before taking VAST ROLD CAPSULE.
Avoid consumption of alcohol while taking VAST ROLD CAPSULE as it may increase the risk of stomach bleeding and aggravate your existing condition.
VAST ROLD CAPSULE is not recommended for use in patients having moderate-to-severe kidney disease and VAST ROLD CAPSULE should be used with caution in patients with kidney problems. Consult your doctor before taking VAST ROLD CAPSULE.
VAST ROLD CAPSULE is not recommended for use in patients having severe liver disease and active liver disease (including persistent elevations of serum transaminases exceeding three times the upper limit) and VAST ROLD CAPSULE should be used with caution in patients with history of liver disease. Consult your doctor before taking VAST ROLD CAPSULE.
Do not take VAST ROLD CAPSULE if you are allergic to Clopidogrel, Rosuvastatin, Aspirin or prostaglandin synthetase inhibitors (Ex. naproxen, ibuprofen, mefenamic acid and indomethacin).
VAST ROLD CAPSULE should be used with caution in patients with interstitial lung disease or severe respiratory failure. Consult your doctor before taking VAST ROLD CAPSULE.
VAST ROLD CAPSULE is not recommended for use in patients with recent ischemic stroke. Consult your doctor before taking VAST ROLD CAPSULE.
VAST ROLD CAPSULE is not recommended for use if you:
Have or had any repeated or unexplained muscle pains
Have family history of hereditary muscular disorders
Have family history of muscle problems following treatment with cholesterol-lowering medicines
Have an underactive thyroidland
Haveastrointestinal problems (such as peptic ulcer or bleeding in theut)
Have bleeding disorders (Ex. bleeding in the brain, hemophilia or others)
Have thrombocytopenia (decreased platelet count)
Have lactose intolerance
Have menorrhagia (abnormally heavy bleeding during menstruation)
Before taking VAST ROLD CAPSULE, inform your doctor if you have:
Upcoming planned surgery (including dental surgery)
Use in pediatrics:
VAST ROLD CAPSULE is strictly not recommended for use in children under 6 years of age andenerally not recommended for use in children and adolescents (under 18 years of age) unless prescribed by your physician due to increased risk of bleeding. Consult your doctor before taking VAST ROLD CAPSULE.
VAST ROLD CAPSULE should be used with caution in elderly patients (aged 70 years or above) because of increased risk ofastro-intestinal bleeding and perforation when used for prolonged duration (if prolonged therapy is essential, patients should be reviewed regularly). Consult your doctor before taking VAST ROLD CAPSULE.
A. Drug-Drug interactions:
Before taking VAST ROLD CAPSULE inform to your doctor, if you are taking any of these medicines:
Other anticoagulants (used for blood thinning) Ex. warfarin, coumarin, heparin, phenindione
Other cholesterol-lowering medicines (Ex. clofibrate,emfibrozil, fenofibrate, ezetimibe)
Other non-steroidal anti-inflammatory drugs (Ex. ibuprofen, paracetamol)
Medicines used to treat HIV infection (Ex. ritonavir with lopinavir and/or atazanavir or sofosbuvir with velpatasvir and voxilaprevir)
Selective serotonin reuptake inhibitors (used to treat depression) Ex. fluoxetine, sertraline, paroxetine or fluvoxamine
Medicines used to treat stomach ulcers such as antacids (Ex. aluminium hydroxide, magnesium hydroxide) and proton-pump inhibitors (Ex. omeprazole or esomeprazole)
Medicines used during percutaneous coronary intervention (Ex. abciximab, eptifibatide and tirofiban)
Antibiotics (used to treat bacterial infections) such as macrolides (Ex. azithromycin, erythromycin, roxithromycin and clarithromycin) or fusidic acid
Medicines used to treat epilepsy (Ex. phenytoin, valproic acid)
Medicines used to treat diabetes (Ex. insulin,lipizide,limepiride)
Ciclosporin or tacrolimus (used to preventraft rejection or treat auto-immune disease)
Nicotinic acid (used to treat vitamin b3 deficiency)
Azole antifungal agents (used to treat fungal infection) Ex. clotrimazole, fluconazole
Methotrexate (used to treat cancer or other auto-immune diseases)
Digoxin (used to treat abnormal heart rate)
Darolutamide (used to treat prostate cancer)
Regorafenib (used to treat colon or rectal cancer)
Probenecid or sulfinpyrazone (used to treatout)
Dipyridamole (an antiplatelet medicine)
Lithium (used to treat metal illness)
Corticosteroids (used to treat pain and inflammation) Ex. prednisolone, dexamethasone
Acetazolamide (used to treat or prevent altitude sickness)
Mifepristone (abortion pill)
Metoclopramide (used to treat vomiting)
If you or anyone else take too much of VAST ROLD CAPSULE, contact your doctor immediately oro to a hospital straight away. Overdosage symptoms of VAST ROLD CAPSULE might include increased bleeding, confusion, disorientation, coma, convulsions, vomiting, tinnitus (ringing in the ears), vertigo (spinning sensation), sweating, warm extremities with bounding pulses, increased respiratory rate and hyperventilation.
Drug : Aspirin, Clopidogrel, Rosuvastatin
Pharmacological Category :
Antiplatelets, HMG-CoA reductase inhibitors
Therapeutic Indication :
Acute coronary syndrome, Myocardial infarction, Angina, Stroke
Dosage Forms : Tablet, Capsule
Keep VAST ROLD CAPSULE out of reach of children
Store at room temperature
FAQs ABOUT VAST ROLD CAPSULE
Can VAST ROLD CAPSULE make me bleed more?
Yes. VAST ROLD CAPSULE can increase your tendency to bleed and therefore it should be used with caution in patients having bleeding disorders like hemophilia, bleeding in theut, brain or under the skin or others. While taking VAST ROLD CAPSULE if you experience any symptoms like blood in vomit or urine, coughing up blood, black stools or purple spots under the skin, contact your doctor immediately as it could be a sign of severe internal bleeding.
Can VAST ROLD CAPSULE be taken during periods?
VAST ROLD CAPSULEenerally can increase your tendency to bleed and if taken during periods, it may cause heavy menstrual bleeding. Consult your doctor before taking VAST ROLD CAPSULE. Your doctor might either ask you to discontinue the treatment with VAST ROLD CAPSULE for some time or may suggest an alternative therapy to improve your disease condition.
Can I continue to take VAST ROLD CAPSULE before any planned surgeries?
No. Avoid taking VAST ROLD CAPSULE if you areoing to undergo any surgery (including dental surgery) because this medicine can make you bleed more than usual. Your doctor might either ask you to discontinue the treatment with VAST ROLD CAPSULE for some time or may suggest an alternative therapy to improve your disease condition.
Can VAST ROLD CAPSULE be used in children?
No. VAST ROLD CAPSULE is not recommended for use in children and adolescents (under 18 years) unless prescribed by your physician. VAST ROLD CAPSULE is strictly not recommended for use in children aged less than 6 years due to risk of increased side effects. Consult your doctor before taking VAST ROLD CAPSULE.
Can I try toet pregnant while taking VAST ROLD CAPSULE?
No. VAST ROLD CAPSULE should be discontinued from use if you are trying toet pregnant because, it may cause severe abnormalities to therowing fetus. Also, it is advised that women of child-bearing potential should use suitable contraceptive method to avoid pregnancy while taking VAST ROLD CAPSULE.
Can I consume alcohol while taking VAST ROLD CAPSULE?
No. Avoid consumption of alcohol while taking VAST ROLD CAPSULE as it could aggravate your existing disease condition and increase the risk of bleeding. Before taking VAST ROLD CAPSULE inform your doctor if you are alcoholic or have history of alcohol abuse.
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USEFUL DIAGNOSTIC TESTS
Kidney function test
Liver function test
Complete blood count
Aspirin+Clopidogrel+Rosuvastatin CAPSULE – Drug Information
Aspirin+Clopidogrel+Rosuvastatin CAPSULE : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage
ROSUVASTATIN 10MG+ASPIRIN 75MG+CLOPIDOGREL 75MG