TERLOC 1MG INJECTION contains Terlipressin which belongs to theroup of medicines called Vasopressin Analogues. It is used for the treatment of bleeding oesophageal varices (bleeding from dilated veins in the food pipe leading to your stomach).
Bleeding oesophageal varices occur when swollen veins (varices) in your lower food pipe rupture and bleed. During TERLOC 1MG INJECTION treatment, your doctor may want you to take several blood tests to monitor side effects.
Before receiving TERLOC 1MG INJECTION, inform your doctor if you have any heart or kidney problems, septic shock or poor circulation to your brain or limbs. TERLOC 1MG INJECTION should be used in pregnant women only if your doctor finds it necessary and should be used in breastfeeding women only after discussing the potential risk to your baby.
TERLOC 1MG INJECTION is not recommended for use in children and adolescents due to lack of experience. The most common side effects of receiving TERLOC 1MG INJECTION are headache, temporary stomach pain or diarrhea, pale face or skin, stomach cramps in women, etc. Contact your doctor if any of the symptomset worse over time.
USES OF TERLOC 1MG INJECTION
Treats bleeding oesophageal varices
HOW TERLOC 1MG INJECTION WORKS
TERLOC 1MG INJECTION reduces bleeding by releasing substance called lysine vasopressin that acts on the walls of the blood vessels and constricts them, thus decreasing the blood flow to the affected veins.
DIRECTIONS FOR USE
TERLOC 1MG INJECTION will beiven to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration of treatment depending upon your age, body weight and disease condition.
SIDE EFFECTS OF TERLOC 1MG INJECTION
Very slow heart rate, high or low blood pressure
Signs in ECG showing insufficient blood supply in the heart vessels
Insufficient blood supply in arms, legs and skin
Paleness of face or skin
Temporary stomach cramps or diarrhoea
Abdominal cramps in women
Chest pain, rapid rise in blood pressure, heart attack, throbbing sensation
Skin or lips becoming bluish
Hot flushes, heart failure
Excess fluid on the lungs, breathlessness due to spasm in the bronchial muscles
Temporary nausea or vomiting
Inflammation of the lymph vessels
Reduced blood supply to the intestines
Uterine cramps, reduced blood flow to the uterus
Too little sodium in the blood if not monitored
Stop receiving TERLOC 1MG INJECTION and contact your doctor immediately if you experience any of the following side effects:
Severe breathlessness due to an asthma attack
Severe trouble with or stopping breathing
Severe pain in the chest, severe and persistent irregular heartbeats
Locally dead skin (necrosis)
HOW TO MANAGE SIDE EFFECTS
Drink lots of fluids, such as water or fruit juice for hydration. Do not consume any medicine on your own without asking your doctor. If symptom persists, contact your doctor.
Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad on your stomach. If symptom persists, contact your doctor.
Try to take rest in a quiet dark room. Don’t involve yourself in exertive activities. Apply a pain-relieving balm on your forehead. If symptom persists, contact your doctor.
WARNING & PRECAUTIONS
TERLOC 1MG INJECTION should be used in pregnant women only if considered clearly necessary. Consult your doctor for advice.
TERLOC 1MG INJECTION should be used in breastfeeding women only after discussing the potential risk to your baby. Consult your doctor for advice.
DRIVING AND USING MACHINES
It is not studied whether TERLOC 1MG INJECTION affects the ability to drive and use machines. Consult your doctor if you feel any side effect during treatment with TERLOC 1MG INJECTION that may stop you from driving or using machines.
TERLOC 1MG INJECTION should be taken with caution in patients with impaired kidney function. Consult your doctor for advice.
No dose adjustment of TERLOC 1MG INJECTION is required in patients with liver failure. Consult your doctor for advice.
Do not receive TERLOC 1MG INJECTION if you are allergic to Terlipressin or any of the other ingredients of this medicine.
TERLOC 1MG INJECTION should be used with caution in patients having bronchial asthma or other conditions that affect your breathing. Consult your doctor for advice.
TERLOC 1MG INJECTION should be used in caution in patients having uncontrolled high blood pressure, insufficient blood circulation in the heart vessels (Ex. angina), arteriosclerosis (hardening of the arteries), irregular heartbeats or in those who previously had a heart attack. Consult your doctor for advice.
Before receiving TERLOC 1MG INJECTION, inform your doctor if you have:
A severe infection called septic shock
Poor blood circulation to your brain (Ex. stroke) or to your legs (peripheral vascular disease)
Disturbances in electrolyte levels in your blood
Decreased amount of fluid in your circulation or have already lost a large amount of blood
Use in Paediatrics:
TERLOC 1MG INJECTION is not recommended for use in children and adolescents due to lack of experience. Consult your child’s doctor for advice.
TERLOC 1MG INJECTION should be used with caution in elderly patients (aged above 70 years). Consult your doctor for advice.
A. Drug – Drug interactions:
Before receiving TERLOC 1MG INJECTION, inform your doctor if you are taking any of the following medicines:
Medicines used to lower high blood pressure (Ex. atenolol, sotalol, furosemide, spironolactone)
Medicines used to induce anaesthesia (Ex. sufentanil, propofol)
Medicines used to treat irregular beating of the heart (Ex. quinidine, procainamide, disopyramide, amiodarone, ibutilide, dofetilide)
Erythromycin (used to treat bacterial infections)
Medicines used to treat allergies (Ex. chlorphenamine, promethazine)
Certain medicines used to treat depression (Ex. nortriptyline, amitriptyline)
TERLOC 1MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
Drug : Terlipressin
Pharmacological Category : Vasopressin Analogue
Therapeutic Indication : Bleeding oesophageal varices
Dosage Forms : Injection
Keep TERLOC 1MG INJECTION out of reach of children
Store in a refrigerator at 2-8°C
FAQs ABOUT TERLOC 1MG INJECTION
Is TERLOC 1MG INJECTION safe for use during pregnancy?
TERLOC 1MG INJECTION should only be used during pregnancy if it is necessary to treat your condition. If you are pregnant, think you may be pregnant or are planning for a baby, contact your doctor before receiving it.
What if I miss a dose of TERLOC 1MG INJECTION?
Please stick to the prescribed schedule as agreed with your doctor for optimal efficacy of TERLOC 1MG INJECTION treatment. Tell your doctor whenever you forget to receive any dose.
Is TERLOC 1MG INJECTION suitable for children?
TERLOC 1MG INJECTION is not recommended for use in children and adolescents due to lack of experience. Consult your child’s doctor for advice. The doctor will advise a proper dose or select a suitable alternative treatment for your child.
Can TERLOC 1MG INJECTION be stopped?
Continue receiving TERLOC 1MG INJECTION until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Contact your doctor in such case.
Can I take other medicines with TERLOC 1MG INJECTION?
Before receiving TERLOC 1MG INJECTION, inform your doctor if you are taking, have taken or areoing to take any other medicine, including prescription, over the counter or any herbal product, as these might lead to serious side effects by interacting with each other.
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2. LoannouN, Doust J, Rockey DC. Terlipressin for acute esophageal variceal hemorrhage. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. January 2003. [Accessed on 6th December 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017851/
3. Aga Khan University. Short course Terlipressin for Control of Acute Variceal Bleeding. NIH U.S. National Library of Medicine. ClinicalTrials.gov. [Revised in September 2008] [Accessed on 6th December 2022]. https://clinicaltrials.gov/ct2/show/NCT00369694
4. Altan Pharmaceuticals, S.A. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 6th December 2022]. https://www.medicines.org.uk/emc/files/pil.9336.pdf
5. FerringmbH. Health Products Regulatory Authority (HPRA). [Revised in April 2020] [Accessed on 6th December 2022]. http://www.hpra.ie/img/uploaded/swedocuments/187421c9-f05f-4a75-9049-3506d3adc33a.pdf
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