OSTA D3 600000iu Injection 1ml
Calcitriol (Vitamin D) 600000 IU
OSTA D3 600000IU contains Calcitriol which belongs to the class of medications called vitamin D analogs. It acts in the body in a similar manner to Vitamin D. Calcitriol is indicated in the management of hypocalcemia in patients undergoing chronic renal dialysis. It significantly reduces elevated parathyroid hormone levels. It has reduction of PTH results in an improvement in renal osteodystrophy.
It increases the amount of calcium in the blood by increasing absorption of calcium from the intestines, reducing any loss of calcium from the kidneys and reduces levels of serum parathyroid hormone. It is not recommended for use in children and adolescents under18 years of age. Inform your doctor if you are taking medicines containing vitamin D, pregnant, breastfeeding or having any serious kidney or liver disease.
USES OF OSTA D3 600000IU
Treats hypocalcaemia in patients undergoing chronic renal dialysis
Reduces elevated parathyroid hormone levels
HOW OSTA D3 600000IU WORKS
OSTA D3 600000IU elevates the plasma levels of calcium by stimulating intestinal calcium uptake, increasing reabsorption of calcium by the kidneys, and possibly increasing the release of calcium from skeletal stores. It works by helping the body to use more of the calcium found in foods or supplements and regulating the body’s production of parathyroid hormone.
DIRECTIONS FOR USE
Your doctor or nurse will administer this medicine by intravenous injection. Your doctor will decide the correct dose for you depending upon your condition.
SIDE EFFECTS OF OSTA D3 600000IU
Skin rash or hives
Shortness of breath
Difficulty in swallowing or breathing
Nausea, vomiting, constipation
Loss of appetite
Muscle or bone pain
Feeling tired or weak
Urge to urinate than normal
Sensitivity to light or changes in vision
Decreased sexual drive
Urinary tract infections
HOW TO MANAGE SIDE EFFECTS
Try taking this medicine with, or just after meal and stick to simple meals. Do not eat rich or spicy food.
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.
Eat fruits, vegetables whole grains and high rich fiber foods.
WARNING & PRECAUTIONS
OSTA D3 600000IU should be used with caution in pregnant women. Consult your doctor for advice.
OSTA D3 600000IU should be used with caution in breastfeeding women. Consult your doctor for advice.
OSTA D3 600000IU should be used with caution in patients with severe kidney disease. Consult your doctor for advice.
Tell your doctor if you are allergic (hypersensitive) to Calcitriol.
Inform your doctor before taking this medicine, if you have,
Hypercalcemia (increased levels of calcium levels in blood)
Had any organ transplant
Problems with your bones (osteoporosis)
Are undergoing dialysis
Talk to your doctor, if you are taking,
Medicines used to treat heartburn and indigestion (magnesium containing antacids)
Medicines containing Vitamin D or vitamin D analogues (e.g. ergocalciferol, cholecalciferol)
Medicines used to treat heart conditions (e.g. digitalis)
Medicines used to treat epilepsy (barbiturates and anticonvulsant)
Corticosteroids (e.g. prednisone and cortisone)
Medicines used to treat high blood pressure or kidney problems (e.g. diuretics)
Pharmacological Category : Vitamin D Analog
Therapeutic Indication :
Hypoparathyroidism/pseudohypoparathyroidism, Secondary hyperparathyroidism (chronic kidney disease)
Dosage Forms : Capsule, Injection, Ointment
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT OSTA D3 600000IU
Does OSTA D3 600000IU affect kidneys?
It may have some effect on the kidney, decreasing urinary loss of calcium by stimulating reabsorption. It acts directly on the parathyroid gland, regulating calcium receptor levels.
How OSTA D3 600000IU works?
It increases the amount of calcium in the blood by increasing absorption of calcium from the intestines, reducing any loss of calcium from the kidneys and reduces levels of serum parathyroid hormone.
1. Peter A. Friedman. Agents affecting mineral ion Homeostatsis and Bone Turnover. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, McGraw-Hill Medical 2011. Page -1291.
2. KD Tripathi MD. Hormones and Related drugs: Thyroid Hormones and Thyroid Inhibitors. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page –338.
3. M. Kitaoka, N.Onoda, H. Kitamura, F. Koiwa, M.Tanaka &M. Fukagawa. Percutaneous Calcitriol injection therapy (PCIT) for secondary hyperparathyroidism: multicentre trial. Nephrology Dialysis Transplantation, 2003; [Accessed 29th Oct 2020]
4. AbbVie Pty Ltd; 2012 [Accessed 29th Oct 2020] https://gp2u.com.au/static/pdf/C/CALCIJEX-CMI.pdf
5. Abbott Laboratories, 2012; Inc. Hospira; U.S. Food & Drug Administration; [Accessed 29 Oct 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/018874s022lbl.pdf
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