OCANAT 10 Tablet 10’s

US$31.00US$43.00 (-28%)

In stock

Compare

OCANAT 10 Tablet 10’s

 Obeticholic Acid 10 mg

OCANAT 10 contains Obeticholic acid which belongs to the group of medicines called Farnesoid X receptor agonists. It is used to treat primary biliary cholangitis (also known as primary biliary cirrhosis) in adults, either by itself or together with other medicine (called ursodeoxycholic acid).

Primary biliary cholangitis is a chronic disorder in which the bile ducts in your liver are slowly destroyed. When these ducts are destroyed, bile (fluid that aids in digestion and absorption of vitamins) builds up in the liver leading to inflammation and scarring. It is also known as primary biliary cirrhosis.

OCANAT 10 is not recommended for use in pregnant women and consult your doctor before taking OCANAT 10 if you are breast-feeding women. OCANAT 10 is not recommended for use in children and adolescents (under 18 years of age) and should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking OCANAT 10.

Prior to treatment with OCANAT 10 your doctor may advice you to take blood test to understand your existing condition like liver function. The most common side effects of taking OCANAT 10 are stomach pain, tiredness, dizziness, constipation, dry skin and fast or irregular heartbeat. Consult your doctor if any of the symptom worsens.

USES OF OCANAT 10
Treats primary biliary cholangitis in adults
HOW OCANAT 10 WORKS

OCANAT 10 works by reducing the production and build-up of bile in the liver and also reduces the inflammation of the liver. Therefore, as a result it helps to improve liver function.

DIRECTIONS FOR USE

Take OCANAT 10 as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF OCANAT 10
COMMON
Stomach pain
Feeling tired
Itching of skin
Thyroid hormone irregularity
Dizziness
Fast or irregular heartbeat (palpitations)
Pain in the mouth and throat
Constipation
Dry skin
Dryness, irritation, redness, crusting or drainage of the skin (eczema)
Rash
Pain in joints
Swelling in the hands and feet
Fever
RARE

Stop taking OCANAT 10 and contact your physician immediately if you experience any of the following side effects:

Severe itching (pruritus)
Worsening of liver problems (symptoms include swelling of stomach-area due to fluid build-up, yellowing of your skin or white of the eyes, black, tarry, or bloody stools, coughing up or vomiting blood, or your vomit looks like coffee grounds, mental changes such as confusion, sleepier than usual or harder to wake up, slurred speech, mood swings, or changes in personality)
Severe symptoms such as stomach-area pain, nausea, vomiting, diarrhoea, loss of appetite or weight loss, new or worsening fatigue, weakness, fever, and chills, light-headedness, less frequent urination
HOW TO MANAGE SIDE EFFECTS

Stomach pain:

Try to take rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.

Constipation:

Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom gets worse.

Dizziness:

Try to rest and relax and get enough sleep. Try to avoid driving or operating any tools or machines while you are feeling dizzy. Limit your consumption of alcohol, as it can aggravate your dizziness. Consult and inform your doctor if the symptom does not improve.

Tiredness:

Drink plenty of fluids and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if the symptom does not improve.

Skin rash:

Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom worsens.

WARNING & PRECAUTIONS
PREGNANCY

OCANAT 10 is not recommended for use in pregnant women. Consult your doctor before taking OCANAT 10.

BREASTFEEDING

It is not known whether OCANAT 10 passes through breast milk. Consult your doctor before taking OCANAT 10.

DRIVING AND USING MACHINES

OCANAT 10 has no or negligible influence on your ability to drive or use machines.

LIVER

OCANAT 10 is not recommended for use in patients with complete blockage of the biliary tract (liver, gall bladder and bile ducts). Consult your doctor before taking OCANAT 10.

ALLERGY

Do not take OCANAT 10 if you are allergic to Obeticholic acid or any of the other ingredients of this medicine.

OTHERS

Before taking OCANAT 10 inform your doctor if you:

Have itching that is difficult to tolerate

Use in paediatrics:

OCANAT 10 is not recommended for use in children and adolescents. Consult child’s doctor for advice.

Use in geriatrics:

OCANAT 10 should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking OCANAT 10.

INTERACTIONS

A. Drug-Drug interactions:

Before taking OCANAT 10, inform your doctor if you are taking any of the following medicines:

Bile acid binding resins such as cholestyramine, colestipol, colesevelam (used to lower blood cholesterol levels)
Theophylline (used to prevent and treat wheezing)
Tizanidine (used to relieve the stiffness and restriction of muscles)
Warfarin (used to prevent and treat blood clots)

Overdosage:

If you or anyone else accidentally take too much of OCANAT 10, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage include yellowing of the skin.

SYNOPSIS
Drug :

Obeticholic acid

Pharmacological Category :

Farnesoid X-receptor agonist

Therapeutic Indication :

Primary Biliary Cholangitis

Dosage Forms :

Tablet

MORE INFORMATION
Keep OCANAT 10 out of reach of children
Store at room temperature
FAQs ABOUT OCANAT 10

Is OCANAT 10 safe to use in patients with liver problems?

OCANAT 10 is not recommended for use in patients with complete blockage of the biliary tract (liver, gall bladder and bile ducts). Consult your doctor before taking OCANAT 10.

What is OCANAT 10 used for?

OCANAT 10 is used to treat primary biliary cholangitis (also known as primary biliary cirrhosis) in adults, either by itself or together with other medicine (called ursodeoxycholic acid).

What common side effects are seen with OCANAT 10?

The most common side effects of taking OCANAT 10 are stomach pain, tiredness, dizziness, constipation, dry skin, fast or irregular heartbeat, fever, swelling in hands and feet, throat and mouth pain, skin rash and itching, joint pain and fever. Consult your doctor if any of the symptom worsens.

Is OCANAT 10 safe to use in pregnant and breast-feeding women?

OCANAT 10 is not recommended for use in pregnant women and it is not known whether OCANAT 10 passes through breast milk. Consult your doctor before taking OCANAT 10 if you are planning to get pregnant or breast-feeding women.

Does OCANAT 10 cause constipation?

Yes, OCANAT 10 may cause constipation in some individuals. To manage this side effect, try taking fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom gets worse.

REFERENCES

1. James E. Barrett. Handbook of Experimental Pharmacology. The pharmacology of bile acids and their receptors. 1st edition. 2019. Page – 13.

2. Frederik Nevens, Pietro Andreone, Giuseppe Mazzella, Simone I Strasser, Christopher Bowlus, Pietro Invernizzi, Joost P H Drenth, Paul J Pockros, Jaroslaw Regula, Ulrich Beuers 1, Michael Trauner, David E Jones, Annarosa Floreani, Simon Hohenester, Velimir Luketic, Mitchell Shiffman, Karel J van Erpecum, Victor Vargas, Catherine Vincent, Gideon M Hirschfield, Hemant Shah, Bettina Hansen, Keith D Lindor, Hanns-Ulrich Marschall, Kris V Kowdley, Roya Hooshmand-Rad, Tonya Marmon, Shawn Sheeron, Richard Pencek, Leigh MacConell, Mark Pruzanski, David Shapiro, POISE Study Group. A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis. NIH. National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 2016. [Accessed on 8th August 2022] https://pubmed.ncbi.nlm.nih.gov/27532829/

3. Intercept Pharmaceuticals. Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (REVERSE). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on March 2008] [Accessed on 8th August 2022] https://clinicaltrials.gov/ct2/show/NCT03439254

4. Almac Pharma Services. Electronic Medicines Compendium (EMC). [Revised in March 2018] [Accessed on 8th August 2022] https://www.medicines.org.uk/emc/files/pil.2561.pdf

5. Intercept Pharmaceuticals, Inc. U.S. Food & Drug Administration. [Revised in January 2018] [Accessed on 8th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/207999s003lbl.pdf

PRODUCT DETAILS

Net Qty
1 N

Item Weight
17.5 g

Ingredient
Obeticholic Acid 10 MG

Hsn Code
30049049
Show more

Additional information

Weight 17.5 g

Only logged in customers who have purchased this product may leave a review.

Reviews

There are no reviews yet.

Price Based Country test mode enabled for testing United States (US). You should do tests on private browsing mode. Browse in private with Firefox, Chrome and Safari

Main Menu

OCANAT 10 Tablet 10's

US$31.00US$43.00 (-28%)

Add to Cart