INTRODUCTION
LAMEZ OD 150MG TABLET contains Lamotrigine which belongs to the group of medicines called Anti-epileptics. It is used along with other medicines to treat epilepsy (phase of uncontrolled electrical signals in the brain, causing seizures).
LAMEZ OD 150MG TABLET is also used in adults for the long-term treatment of bipolar I disorder to prolong the time between mood episodes in people who have been treated for mood episodes with other medicine. Bipolar disorder is a mental disorder that causes extreme mood swings including emotional highs (mania or hypomania) and lows (depression).
Your doctor will monitor your treatment and may advise you to avoid sunlight or protect yourself against the sun (Ex. use of a sunscreen and to wear protective clothing).
Before taking LAMEZ OD 150MG TABLET, inform your doctor if you have or had depression, heart problems or mood disorders, if you had aseptic meningitis after taking LAMEZ OD 150MG TABLET or if you are taking pills to prevent pregnancy.
LAMEZ OD 150MG TABLET should be used with caution in pregnant or breastfeeding women. LAMEZ OD 150MG TABLET is not recommended for use for children (under 2 years of age) so, consult your child’s doctor for advice.
Patients taking LAMEZ OD 150MG TABLET may have thoughts of self-harm. If at any time you have these thoughts, immediately see your doctor. The most common side effects of taking LAMEZ OD 150MG TABLET are dizziness, shaking, headache, diarrhea, sleep or vision problems, rash, etc. Call your doctor if any of the symptoms get worse.
USES OF LAMEZ OD 150MG TABLET
LAMEZ OD 150MG TABLET treats:
Epilepsy
Bipolar I disorder
HOW LAMEZ OD 150MG TABLET WORKS
LAMEZ OD 150MG TABLET likely works similarly in bipolar disorder, as it does in reducing seizures. It acts by inhibiting sodium currents (which is out of control in epileptic patients) via suppression of the release of glutamate (an excitatory brain chemical).
DIRECTIONS FOR USE
Take LAMEZ OD 150MG TABLET as advised by your physician. You can take it with meals or on an empty stomach.
For Tablet:Â Swallow LAMEZ OD 150MG TABLET with a glass of water. Do not crush or chew it.
For Dispersible Tablet: Disperse LAMEZ OD 150MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide a proper dose and duration of therapy for you according to your age, body weight and disease condition. Continue to take LAMEZ OD 150MG TABLET for the prescribed duration to achieve better results. Do not stop taking LAMEZ OD 150MG TABLET unless your doctor advises you to stop.
SIDE EFFECTS OF LAMEZ OD 150MG TABLET
COMMON
Dizziness, headache
Sleepiness or lack of sleep
Shaking, lack of coordination
Back pain, tiredness
Nausea, vomiting, stomach pain
Diarrhea, dry mouth
Rash
Blurred or double vision
Fever, stuffy nose, sore throat
Infections (including seasonal flu)
UNCOMMON
Unusual hair loss or thinning (alopecia)
Skin rashes or sunburn after exposure to sun or artificial light (photosensitivity)
RARE
Conjunctivitis (itchy eyes with discharge, crusty eyelids)
Meningitis (symptoms including fever, nausea, vomiting, headache, stiff neck and extreme sensitivity to bright light)
Nystagmus (rapid and uncontrollable eye movements)
Stevens-Johnson syndrome (a life-threatening skin reaction)
Stop taking LAMEZ OD 150MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Serious skin reaction (skin rash, blistering or peeling, hives, painful sores in your mouth or around your eyes)
Blood or liver problems (fever, frequent infections, severe muscle pain, swollen face, eyes, lips, tongue or lymph nodes, unusual bruising or bleeding, paleness, weakness, fatigue, yellow skin or eyes, trouble walking or seeing, fits for the first time or happening more often, pain or tenderness in upper stomach area)
Heartbeat problems (fast, slow or pounding heartbeat, feel your heart skip a beat, breathlessness, chest pain, lightheadedness)
(Suicidal ideas or attempt, new or worsening depression, anxiety or irritability, agitation or restlessness, aggression, anger or violence, acting on dangerous impulses, panic attacks, trouble sleeping, extremely increased activity and talking, other unusual changes in behavior or mood)
Aseptic meningitis (headache, fever, nausea, vomiting, stiff neck, rash, unusual light sensitivity, muscle pains, chills, confusion, drowsiness)
HOW TO MANAGE SIDE EFFECTS
Nausea:
Take LAMEZ OD 150MG TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.
Vomiting:
Get adequate rest. Drink lots of fluids, especially water. Have small sips if you feel sick. Eat when you feel like it – no need to eat or avoid any specific foods. If symptom persists, contact your doctor.
Diarrhea:
Drink fluids such as water or fruit juices so that you are sufficiently hydrated. If symptom persists, contact your doctor.
Dry mouth:
Sip water regularly and other sugar free liquids. Do not use alcohol-containing mouthwashes because they can make your mouth dry, use the one that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. If symptom persists, contact your doctor.
Headache:
Drink plenty of water and get adequate rest. Try to be relaxed and stress free. Take medicine for headache after asking your doctor. If symptom persists, contact your doctor.
Dizziness:
Lie down until dizziness gets better, then gradually get up. Don’t hurry and move slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. If symptom persists, contact your doctor.
Skin rash:
Avoid hot showers to prevent further irritation of skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. If symptom persists, contact your doctor.
Blurred vision:
Do not drive or go outside on your own if you have blurred eyesight. Close your eyes for some time until you have a clear vision. Call your doctor if your vision remains blur for a long period.
WARNING & PRECAUTIONS
PREGNANCY
LAMEZ OD 150MG TABLET should be used with caution in women who are pregnant or planning to have a baby. Consult your doctor before taking it.
BREASTFEEDING
LAMEZ OD 150MG TABLET should be used with caution in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you experience dizziness, sleepiness and other symptoms and signs of central nervous system depression after taking LAMEZ OD 150MG TABLET.
KIDNEY
LAMEZ OD 150MG TABLET should be taken with caution in patients with kidney impairment. Consult your doctor before taking it.
LIVER
LAMEZ OD 150MG TABLET should be taken with caution in patients with moderate to severe liver problems. Consult your doctor before taking it.
ALLERGY
Do not take LAMEZ OD 150MG TABLET if you are allergic to Lamotrigine or any of the other ingredients of this medicine. Inform your doctor if you had a rash or allergic reaction to another antiepileptic medicine.
HEART DISEASE
LAMEZ OD 150MG TABLET should be taken with caution in patients with a personal or family history of heart problems or irregular heartbeats, including genetic abnormalities. Consult your doctor before taking it.
OTHERS
Before taking LAMEZ OD 150MG TABLET, inform your doctor if you:
Have or had depression, suicidal ideas or behavior or mood problems
Had aseptic meningitis after taking LAMEZ OD 150MG TABLET
Use in pediatrics:
LAMEZ OD 150MG TABLET is not recommended for use in children (under 2 years of age). Consult your child’s doctor for advice.
Use in geriatrics:
LAMEZ OD 150MG TABLET should be used with caution in elderly patients (aged above 75 years). Consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions:
Before taking LAMEZ OD 150MG TABLET, inform your doctor if you are taking any of the following medicines:
Medicines used to treat epilepsy and mental health problems (Ex. oxcarbazepine, phenobarbital, primidone, phenytoin, valproate)
Medicines used for HIV treatment (Ex. lopinavir, ritonavir, atazanavir, ritonavir)
Medicines used to prevent pregnancy (Ex. ethinylestradiol, levonorgestrel)
Rifampin (used for bacterial infections like tuberculosis)
Overdosage:
If you or anyone else accidentally take too much of LAMEZ OD 150MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of LAMEZ OD 150MG TABLET overdose are disturbed coordination, balance and speech, rapid uncontrolled eye movements, fits and decreased level of consciousness.
SYNOPSIS
Drug :Â Â Lamotrigine
Pharmacological Category :Â Â Phenyltriazine Antiepileptics
Therapeutic Indication :Â Â Epilepsy, Bipolar disorder
Dosage Forms :Â Â Tablet, Dispersible tablet
MORE INFORMATION
Keep LAMEZ OD 150MG TABLET out of reach of children
Store LAMEZ OD 150MG TABLET below 25°C
FAQs ABOUT LAMEZ OD 150MG TABLET
Can I take LAMEZ OD 150MG TABLET if I am taking oral contraceptives?
Women taking LAMEZ OD 150MG TABLET should inform their doctor if they are planning to start or stop use of oral contraceptives or other female hormonal preparations, as it might affect blood levels of LAMEZ OD 150MG TABLET. Also, promptly inform your doctor if you experience adverse reactions or changes in menstrual pattern (Ex. break-through bleeding) while taking LAMEZ OD 150MG TABLET along with the contraceptive pills.
Can I stop taking LAMEZ OD 150MG TABLET?
Do not stop taking LAMEZ OD 150MG TABLET without talking to your doctor. Stopping LAMEZ OD 150MG TABLET suddenly may cause serious problems like unstoppable seizures. Talk with your doctor about how to stop LAMEZ OD 150MG TABLET slowly.
Is LAMEZ OD 150MG TABLET safe to take during breastfeeding?
Breastfeeding women should know that LAMEZ OD 150MG TABLET is present in breast milk and they should monitor their child for potential adverse effects of this medicine (Ex. difficulty breathing, episodes of temporarily stopping breathing, poor sucking or sleepiness). Discuss the benefits and risks of continuing breastfeeding with your doctor before taking LAMEZ OD 150MG TABLET.
Are there any side effects to look out for, while taking LAMEZ OD 150MG TABLET?
During treatment with LAMEZ OD 150MG TABLET, look out for signs and symptoms like fever, rash, lymphadenopathy, irregular heartbeat, new or worsening of depression, any unusual changes in mood or behavior, suicidal thoughts or behavior or thoughts about harming yourself. You or your caregivers should immediately report concerned behaviors to your doctor.
What if I forget to take a dose of LAMEZ OD 150MG TABLET?
If you forget to take a dose of LAMEZ OD 150MG TABLET, do not take it two times to make up for the missed dose. If you miss a dose, it is important that you ask your doctor for advice on how to start taking the medicine again.
REFERENCES
1. Brunton L.L., Hilal-Dandan R, Knollmann B.C. Pharmacotherapy of the Epilepsies. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. Thirteenth Edition. 2017. Page – 316.
2. KD. Tripathi. Antiepileptic drugs. Essentials of Medical Pharmacology. Eighth edition. 2019. Page – 445.
3. Felicity Ng, Karen Hallam, Nellie Lucas and Michael Berk. The role of lamotrigine in the management of bipolar disorder. NIH National Library of Medicine, National center for biotechnology information. Pubmed central. August 2007. [Accessed on 27th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655087/
4. Ebrahimi HA, Ebrahimi F. The effect of lamotrigine on epilepsy. NIH National Library of Medicine, National center for biotechnology information. Pubmed central. 2012. [Accessed on 27th May 2022]Â https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829260/
5. Generics [UK] Ltd. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 27th May 2022]Â https://www.medicines.org.uk/emc/files/pil.8565.pdf
6. Delpharm Poznan Spólka Akcyjna. Electronic Medicines Compendium (EMC). [Revised in June 2022] [Accessed on 27th May 2022] https://www.medicines.org.uk/emc/files/pil.1286.pdf
7. GlaxoSmithKline. Lamictal (Lamotrigine tablets). [Revised in April 2022] [Accessed on 27th May 2022]Â https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Lamictal/pdf/LAMICTAL-PI-MG.PDF
Net Qty
1 N
Item Weight
17.5 g
Ingredient
Lamotrigine Sr 150 MG
Hsn Code
30049081
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