INTRODUCTION
FERTITRIG 50 TABLET contains Clomiphene which belongs to the group of medicines called Ovulation Stimulators. It is used in the treatment of female infertility. It can promote ovulation (release of matured egg from the ovaries) in women who do not produce eggs and in women undergoing fertility treatments.
Prior to the treatment, your doctor may evaluate your fertility status thoroughly as a precaution. During treatment with FERTITRIG 50 TABLET, your doctor will closely monitor your health condition through several blood tests and ultrasounds to avoid the risk of side effects.
Before taking FERTITRIG 50 TABLET inform your doctor if you have any problems in your kidney or liver. You must also inform your doctor if you have fits, high blood fat levels, unexplained vaginal bleeding, early menopause, cyst in the ovaries or cancer in the breast, uterus or ovaries as a precaution.
FERTITRIG 50 TABLET should not be used in pregnant women after successful conception. It is also not recommended for use in breastfeeding women and in children or adolescents (aged below 18 years).
The most common side effects of taking FERTITRIG 50 TABLET are flushing, lower stomach pain, nausea, vomiting, painful periods, heavy bleeding, painful breasts and bloating. Consult your doctor if they worsen.
USES OF FERTITRIG 50 TABLET
Treats female infertility
Promotes ovulation (release of matured egg from ovaries)
HOW FERTITRIG 50 TABLET WORKS
FERTITRIG 50 TABLET is an ovulation stimulator. It makes your body release the sufficient amount of hormones that stimulates the release of matured eggs from the ovaries (ovulation). This may help women to become pregnant easily.
DIRECTIONS FOR USE
Take FERTITRIG 50 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not chew or crush the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF FERTITRIG 50 TABLET
COMMON
Flushing
Lower stomach pain with weight gain and swelling
Nausea, vomiting
Painful periods
Heavy bleeding during periods
Bleeding in between periods
Breast pain
Bloating, distended stomach
Increased blood fat levels
UNCOMMON
Nervousness
Feeling dizzy, problems in balance
Tiredness
Difficulty in falling asleep (insomnia)
Depression, mood changes, changes in behaviour
RARE
Fits
Eye pain, reduced vision
Stop taking FERTITRIG 50 TABLET and contact your doctor immediately if you experience any of the following side effects:
Signs of ovarian hyperstimulation syndrome (such as lower abdominal pain with sensation of nausea or vomiting, weight gain, difficulty in breathing, difficulty in passing urine, enlarged ovaries and fluid build-up in chest or abdomen)
Signs of allergic reactions (such as skin rash, itching, swelling of the eyes, face, lips, tongue or throat leading to difficulty in breathing or swallowing)
Signs of a stroke (such as weakness, numbness, or paralysis on one side of the body, slurred speech, sudden blurred vision, unsteadiness or confusion)
Blurred vision or flashes or spots in front of the eyes
Sings of liver problems causing yellowing of eyes and skin (jaundice)
Sudden severe headaches
Mental illness like psychosis
HOW TO MANAGE SIDE EFFECTS
Nausea and Vomiting:
Take FERTITRIG 50 TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.
WARNING & PRECAUTIONS
PREGNANCY
FERTITRIG 50 TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
BREASTFEEDING
FERTITRIG 50 TABLET can reduce breast milk production. Therefore, consult your doctor before taking FERTITRIG 50 TABLET if you are a breastfeeding woman.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you experience any vision problems (like blurred vision) after taking FERTITRIG 50 TABLET.
KIDNEY
FERTITRIG 50 TABLET should be used with caution in patients having kidney problems. Therefore, consult your doctor before taking it.
LIVER
FERTITRIG 50 TABLET is not recommended for use in patients who have or ever had any liver problems in the past. Therefore, consult your doctor before taking it.
ALLERGY
Do not take FERTITRIG 50 TABLET if you are allergic to Clomiphene.
OTHERS
FERTITRIG 50 TABLET is not recommended for use if you have:
An unusual menstrual bleeding with unknown cause
Breast cancer, uterine cancer or ovarian cancer
Ovarian cyst
Before taking FERTITRIG 50 TABLET, inform your doctor if you have:
Or ever had fits or seizures
Fibroids in womb
Polycystic ovaries
Swollen or enlarged ovaries
Or have a family history of hypertriglyceridemia (high fat content in blood)
An early menopause
Use in pediatrics:
FERTITRIG 50 TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use in geriatrics:
FERTITRIG 50 TABLET is for use only in patients who undergo menstruation. It is not intended for use in men or in elderly women who have reached menopause.
INTERACTIONS
A. Drug – Drug interactions:
Before taking FERTITRIG 50 TABLET, inform your doctor if you are taking any other medicines including other prescription, non-prescription or herbal medicines.
Overdosage:
If you or anyone else accidentally took more FERTITRIG 50 TABLET, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
Drug : Clomiphene
Pharmacological Category : Selective Estrogen Receptor Modulator
Therapeutic Indication : Female Infertility, Promotes Ovulation
Dosage Forms : Tablet, Capsule
MORE INFORMATION
Keep FERTITRIG 50 TABLET out of reach of children
Store FERTITRIG 50 TABLET below 25°C
FAQs ABOUT FERTITRIG 50 TABLET
What is the use of FERTITRIG 50 TABLET?
FERTITRIG 50 TABLET is used in the treatment of female infertility. It can promote ovulation (release of matured egg from the ovaries) in women who do not produce eggs and in women undergoing fertility treatments.
How FERTITRIG 50 TABLET works?
FERTITRIG 50 TABLET is an ovulation stimulator. It makes your body release the sufficient amount of hormones that stimulates the release of matured eggs from the ovaries (ovulation). This may help women to become pregnant easily.
How to take FERTITRIG 50 TABLET?
Take FERTITRIG 50 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not chew or crush the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
What precautions must be followed while taking FERTITRIG 50 TABLET?
Before taking FERTITRIG 50 TABLET inform your doctor if you have any problems in your kidney or liver. You must also inform your doctor if you have fits, high blood fat levels, unexplained vaginal bleeding, early menopause, cyst in the ovaries or cancer in the breast, uterus or ovaries as a precaution. FERTITRIG 50 TABLET should not be used in pregnant women after successful conception. Regularly visit your doctor and perform all blood tests and ultrasounds recommended by him/her without fail.
Is FERTITRIG 50 TABLET safe?
FERTITRIG 50 TABLET is considered safe at the doses administered by the physician. However, consult your doctor if you experience any unusual side effects.
What are the common side effects of taking FERTITRIG 50 TABLET?
The most common side effects of taking FERTITRIG 50 TABLET are flushing, lower stomach pain, nausea, vomiting, painful periods, heavy bleeding, painful breasts and bloating. Consult your doctor if they worsen.
Can I use FERTITRIG 50 TABLET during pregnancy?
FERTITRIG 50 TABLET should not be used in pregnant women after successful conception. Therefore, consult your doctor for advice.
Can FERTITRIG 50 TABLET be used in children?
FERTITRIG 50 TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice.
Will taking a higher dose of FERTITRIG 50 TABLET be more effective?
No, taking a higher dose of FERTITRIG 50 TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
What happens if I forgot to take a dose of FERTITRIG 50 TABLET?
If you forgot to take a dose of FERTITRIG 50 TABLET, take it as soon as you remember. However, if it is time for the next dose of FERTITRIG 50 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of FERTITRIG 50 TABLET to compensate the missed ones.
Is FERTITRIG 50 TABLET safe to use in kidney disease?
FERTITRIG 50 TABLET should be used with caution in patients with kidney problems. Your doctor will access your health condition and suggest a suitable dose for you.
Can the use of FERTITRIG 50 TABLET affect the liver?
Yes. FERTITRIG 50 TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.
REFERENCES
1. KD. Tripathi. Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology. 7th Edition. 2013. Page – 312.
2. The Practice Committee of the American Society for Reproductive Medicine. Use of clomiphene citrate in infertile women: a committee opinion. Fertility and Sterility. August 2013. [Accessed on 10th November 2022]. https://www.sciencedirect.com/science/article/pii/S0015028213006432
3. Clomiphene. NIH National Library of Medicine, National Centre for biotechnology information. PubChem. October 2022. [Accessed on 10th November 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Clomiphene
4. Sanofi. Electronic Medicines Compendium (EMC). [Revised in June 2021]. [Accessed on 10th November 2022]. https://www.medicines.org.uk/emc/files/pil.961.pdf
5. Patheon France SAS. Health Products Regulatory Authority (HPRA). [Revised in June 2021]. [Accessed on 10th November 2022]. http://www.hpra.ie/img/uploaded/swedocuments/62ee0bc2-beca-4599-9deb-77f927626c4c.pdf
6. Cipla Ltd. FERTOMID Tablets (Clomiphene citrate). Ciplamed. [Revised in November 2020]. [Accessed on 10th November 2022]. https://ciplamed.com/content/fertomid-tablets
7. Central Drugs Standard Control Organization. Clomiphene Citrate B.P. February 1974. [Accessed on 10th November 2022]. https://cdscoonline.gov.in/CDSCO/Drugs
USEFUL DIAGNOSTIC TESTS
Anti-Mullerian Hormone
Glycosylated Haemoglobin
Testosterone Total
Thyroid Stimulating Hormone
Country Of Origin
India
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