INTRODUCTION
ERADIF 3D CREAM is a combination of Clobetasol, Miconazole and Neomycin which belongs to the group of medicines called Corticosteroids, Antifungals and Antibiotics. It is used to treat resistant dermatoses (skin infections) with secondary bacterial or fungal infection.
ERADIF 3D CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox) and perforated eardrum. Contact your doctor before applying.
ERADIF 3D CREAM should be used with caution in patients with liver or kidney disease. Â Contact your doctor before applying.
ERADIF 3D CREAM is generally not recommended for use in pregnancy unless considered clearly necessary. ERADIF 3D CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.
ERADIF 3D CREAM is not recommended for use in children under 2 years of age and should be used with caution in children above 2 years of age. Contact your doctor before applying.
Dosage adjustment is not required for ERADIF 3D CREAM in the geriatric population. However, greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying.
The most common side effects of this medicine are skin rash, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.
USES OF ERADIF 3D CREAM
Treats resistant dermatoses (skin infections) with secondary bacterial or fungal infection
HOW ERADIF 3D CREAM WORKS
ERADIF 3D CREAM helps to treat infection, where Clobetasol have anti-inflammatory, antipruritic, and vasoconstrictive properties, which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Miconazole is an antifungal which stops the growth of fungi while Neomycin is an antibiotic which stops the growth of bacteria in the skin.
DIRECTIONS FOR USE
Apply ERADIF 3D CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes, face, groin or in the skin folds.
SIDE EFFECTS OF ERADIF 3D CREAM
COMMON
Skin rash, itching, redness
Burning sensation
Contact dermatitis
RARE
Stop applying ERADIF 3D CREAM and contact your physician immediately if you experience any of the following side effects:
Severe allergic reactions such as anaphylaxis or angioedema (skin rash, swelling of the face, lips, tongue, or throat causing breathing difficulty)
HOW TO MANAGE SIDE EFFECTS
Itchy skin:
Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if itching worsens.
WARNING & PRECAUTIONS
PREGNANCY
ERADIF 3D CREAM is generally not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before applying.
BREASTFEEDING
ERADIF 3D CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.
KIDNEY
ERADIF 3D CREAM should be used with caution in patients with kidney disease. Contact your doctor before applying.
LIVER
ERADIF 3D CREAM should be used with caution in patients with liver disease. Contact your doctor before applying.
ALLERGY
ERADIF 3D CREAM is not recommended for use in patients allergic to clobetasol, miconazole, neomycin, or to other ingredients of this medicine.
OTHERS
ERADIF 3D CREAM is not recommended for use if you have:
Rosacea
Acne vulgaris
Perioral dermatitis
Perianal and genital pruritus
Viral infections (ex. herpes simplex, chickenpox)
Perforated eardrum
Use in pediatrics:
ERADIF 3D CREAM is not recommended for use in children under 2 years of age and should be used with caution in children above 2 years of age. Contact your doctor before applying.
Use in geriatrics:
Dosage adjustment is not required for ERADIF 3D CREAM in the geriatric population. However, greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying.
INTERACTIONS
A. Drug-Drug interactions:
Tell your doctor if you are taking,
Ritonavir (medicines used for HIV infections)
Itraconazole (medicines used for fungal infections)
Aminoglycosides like amikacin, gentamicin (medicines used for bacterial infections)
Neuromuscular blocking agents like atracurium, pancuronium (medicines used in anaesthesia)
Warfarin (medicines used to treat or prevent blood clots)
Overdosage:
If you or anyone else accidentally use too much of ERADIF 3D CREAM, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are skin irritation, Hypothalamic-pituitary adrenal (HPA) axis suppression, cushingoid features (Ex. moon face, central obesity), ear damage and kidney damage may occur.
SYNOPSIS
Drug :Â Â Clobetasol, Miconazole, Neomycin
Pharmacological Category :Â Â Corticosteroids, Antifungals, Antibiotics
Therapeutic Indication :Â Â Skin infections
Dosage Forms :Â Â Cream, Lotion, Ointment
MORE INFORMATION
Keep out of reach of children
Store ERADIF 3D CREAM below 25°C
FAQs ABOUT ERADIF 3D CREAM
Q: What are the possible side effects of applying ERADIF 3D CREAM?
A: The most common side effects of this medicine are skin rash, urticaria, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.
Q: Can I use ERADIF 3D CREAM in children?
A: ERADIF 3D CREAM is not recommended for use in children under 2 years of age and should be used with caution in children above 2 years of age. Contact your doctor before applying.
Q: For what conditions ERADIF 3D CREAM is used?
A: ERADIF 3D CREAM is used to treat resistant dermatoses (skin infections) with secondary bacterial or fungal infection.
Q: Does ERADIF 3D CREAM cause itching on the skin?
A: Yes, ERADIF 3D CREAM may cause skin itching at the site of application as a temporary side effect. However, if the itching persists or worsens, consult your doctor for advice.
Q: Can I stop using ERADIF 3D CREAM when my symptoms are relieved?
A: No, do not stop using ERADIF 3D CREAM and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.
Q: Who should not use ERADIF 3D CREAM?
A: ERADIF 3D CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox), perforated eardrum. Contact your doctor before applying.
REFERENCES
1. K.D. Tripathi. Drugs acting on the skin and mucous membrane, Antifungal Drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895, 792, 750.
2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/5311051
3. Bethesda (MD). Miconazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/4189
4. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin
5. Blue Cross labs. Clobetasol, Miconazole and Neomycin. [Revised on May 2020] [Accessed on 24th June 2022] https://www.bluecrosslabs.com/img/sections/SONADERM-NM-CREAM.pdf
Country Of Origin
India
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