INTRODUCTION
DOXOLON 400 TABLET contains Doxofylline which belongs to theroup of medicines called Bronchodilators. It is used to treat asthma and chronic obstructive pulmonary disease (COPD). It can also be used to reduce apnea (lack of breathing) and other respiratory diseases associated with bronchospasm (tightening of airways).
Asthma is a long-term respiratory disease in which your airways become inflamed, swollen and narrowed. It also causes excessive mucous secretion in the airways which makes it difficult for the air to pass through, leading to unpleasant symptoms like wheezing, difficulty in breathing, chest pain and/or cough.
COPD is a lung disease characterized by chronic lung inflammation and obstructed air flow within the airways. It causes wheezing, breathing difficulties, cough with mucus production and chest pain.
During treatment with DOXOLON 400 TABLET your doctor will periodically monitor the levels of doxofylline in your blood as a precaution and would adjust the dose accordingly. Limit the consumption of caffeine containing foods and beverages (such as coffee) while taking DOXOLON 400 TABLET.
Before taking DOXOLON 400 TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have hypertension, hyperthyroidism, stomach ulcers or any concomitant infections as a precaution.
DOXOLON 400 TABLET is not recommended for use in patients with severe hypotension or heart problems (such as myocardial infarction). It is also not suitable for use in breastfeeding women.
Inform your doctor before taking DOXOLON 400 TABLET if you are pregnant or planning to become pregnant. The most common side effects of taking DOXOLON 400 TABLET are nausea, vomiting, upper stomach pain, irritability, lack of sleep and fast heartbeat or breathing. Consult your doctor if any of these side effect worsens.
USES OF DOXOLON 400 TABLET
It is used to treat:
Bronchial Asthma
Chronic Obstructive Pulmonary Disease (COPD)
Apnea (breathing stops for a brief period)
HOW DOXOLON 400 TABLET WORKS
DOXOLON 400 TABLET is a bronchodilator. It relaxes the smooth muscles of the airways by blocking the release of certain enzymes (phosphodiesterase) in the respiratory tract that triggers narrowing. As a result, it widens the airways, allows the air to pass through more freely and makes breathing easier.
DIRECTIONS FOR USE
Take DOXOLON 400 TABLET as advised by your physician. Swallow the medicine with alass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose, duration of therapy and number of doses per day depending upon your age, body weight and disease condition.
Do not stop taking DOXOLON 400 TABLET once your symptoms subside without consulting your doctor.
SIDE EFFECTS OF DOXOLON 400 TABLET
COMMON
Nausea, vomiting
Upper stomach pain
Headache
Irritability
Lack of sleep (insomnia)
Abnormal or rapid heartbeat
Fast breathing
RARE
Hyperglycemia (high blood sugar levels)
Albuminuria (presence of albumin in urine)
Stop taking DOXOLON 400 TABLET and consult your doctor immediately if you experience any of the following side effects:
Cardiac arrhythmias
Fits (tonic-clonic seizures)
HOW TO MANAGE SIDE EFFECTS
Nausea and Vomiting:
Take DOXOLON 400 TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
WARNING & PRECAUTIONS
PREGNANCY
There is no adequate information regarding the use of DOXOLON 400 TABLET in pregnant women. Therefore, it should be used in pregnant women only if considered necessary by the physician.
BREASTFEEDING
DOXOLON 400 TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
DOXOLON 400 TABLET does not affect your ability to drive or operate machines. However, do not drive or handle any heavy tools or machines if your ability is affected by DOXOLON 400 TABLET.
KIDNEY
DOXOLON 400 TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
LIVER
DOXOLON 400 TABLET should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.
ALLERGY
Talk to your doctor before taking DOXOLON 400 TABLET if you are allergic to Doxofylline or to any other similar medicines (such as etophylline, aminophylline).
HEART DISEASE
DOXOLON 400 TABLET is not recommended for use in patients with heart problems (such as heart attack or myocardial infarction). It should be used with caution in patients with congestive heart failure. Therefore, consult your doctor before taking it.
OTHERS
DOXOLON 400 TABLET is not recommended for use if you:
Have severe hypotension (low blood pressure)
Before taking DOXOLON 400 TABLET tell your doctor if you:
Have concomitant infections
Have hypertension (high blood pressure)
Have severe hypoxemia (low oxygen levels in blood)
Have hyperthyroidism
Have chronic cor pulmonale (right side of the heart fails to function properly)
Have peptic ulcer
Use in Pediatrics:
There is no adequate information regarding the use of DOXOLON 400 TABLET in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.
Use ineriatrics:
DOXOLON 400 TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
INTERACTIONS
A) Drug-Drug Interactions:
Before taking DOXOLON 400 TABLET, inform your doctor if you are taking any of the following medicines such as:
Other methylxanthines (used to treat respiratory problems) Ex. etophylline, aminophylline
Medicines used to treat bacterial infections (such as erythromycin, troleandomycin, lincomycin, clindamycin)
Allopurinol (a medicine used to treatout)
Cimetidine (a medicine used to treat stomach ulcers)
Influenza vaccine
Propranolol (a medicine used to treat heart problems)
Phenytoin (a medicine used to treat fits)
Sympathomimetic drugs (medicines used to increase heart rate and hypertension) Ex. ephedrine
B) Drug-Food Interactions:
Limit the consumption of foods and beverages rich in caffeine (such as coffee) while taking DOXOLON 400 TABLET.
Overdosage:
If you or anyone else accidentally took more DOXOLON 400 TABLET, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
Drug : Doxofylline
Pharmacological Category : Methylxanthines
Therapeutic Indication : Bronchial Asthma, Chronic Obstructive Pulmonary Disease, Apnea
Dosage Forms : Tablet, Syrup, Injection
MORE INFORMATION
Keep DOXOLON 400 TABLET out of reach of children
Store DOXOLON 400 TABLET at room temperature
FAQs ABOUT DOXOLON 400 TABLET
How DOXOLON 400 TABLET works?
DOXOLON 400 TABLET is a bronchodilator. It relaxes the smooth muscles of the airways by blocking the release of certain enzymes (phosphodiesterase) in the respiratory tract that triggers narrowing. As a result, it widens the airways, allows the air to pass through more freely and makes breathing easier.
What is the use of DOXOLON 400 TABLET?
DOXOLON 400 TABLET is used to treat asthma and chronic obstructive pulmonary disease (COPD). It can also be used to reduce apnea (lack of breathing) and other respiratory diseases associated with bronchospasm (tightening of airways).
Can I take DOXOLON 400 TABLET daily?
DOXOLON 400 TABLET isenerally prescribed as two/three doses per day. However, your doctor will decide the number of doses per day depending upon your age, body weight and disease condition.
Is DOXOLON 400 TABLET effective?
Yes. DOXOLON 400 TABLET effectively controls the symptoms of asthma, COPD and other breathing problems, by relaxing the smooth muscles of the airways. As a result, it widens the airways, allows the air to pass through more freely and makes breathing easier
What will happen if I consume a high dose of DOXOLON 400 TABLET than prescribed by my doctor?
Do not consume a higher dose of DOXOLON 400 TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose, is not working for you, consult your doctor for advice.
Is DOXOLON 400 TABLET safe?
DOXOLON 400 TABLET is considered safe at doses prescribed by the physician. However, it may cause few side effects such as stomach pain, headache, nausea, vomiting, irritability, lack of sleep or fast breathing or heart rate in some individuals. Contact your doctor if they bother you.
What should I do if I forgot to take a dose of DOXOLON 400 TABLET?
If you forgot to take a dose of DOXOLON 400 TABLET, take it as soon as possible. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of DOXOLON 400 TABLET to compensate the missed dose.
Will taking a higher dose of DOXOLON 400 TABLET be more effective?
No. Do not take a higher dose of DOXOLON 400 TABLET than prescribed by your doctor, as it could lead to toxicity. Always consume the dose prescribed by your doctor. If you feel that the prescribed dose is not working for you, consult your doctor for advice.
I’m pregnant. Can I take DOXOLON 400 TABLET?
DOXOLON 400 TABLET should be used in pregnant women only if it is considered necessary by the physician. Your doctor will prescribe you with DOXOLON 400 TABLET after evaluating the risks and benefits of the therapy.
Can DOXOLON 400 TABLET be used in children?
There is no adequate information regarding the use of DOXOLON 400 TABLET in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.
Can I stop using DOXOLON 400 TABLET once my symptoms subside?
No. Continue to use DOXOLON 400 TABLET as long as your doctor prescribes it to you. Do not stop using this medicine or reduce the dose suddenly without consulting your doctor as it may make it less effective.
Can DOXOLON 400 TABLET be used on an asthma attack?
No. DOXOLON 400 TABLET is only used to prevent or manage the symptoms of asthma. If your asthma or breathingets worse suddenly, contact your doctor immediately oro to the hospital straight away to avoid further exacerbation of the attack. Meanwhile use a fast-acting rescue inhaler for treating your condition.
How to take DOXOLON 400 TABLET?
Take DOXOLON 400 TABLET as advised by your physician. Swallow the medicine with alass of water. Do not crush or chew the medicine.
What are the side effects of taking DOXOLON 400 TABLET?
The most common side effects of taking DOXOLON 400 TABLET are nausea, vomiting, upper stomach pain, irritability, lack of sleep and fast heartbeat or breathing. Consult your doctor if any of these side effect worsens.
REFERENCES
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of Medical Pharmacology. Page – 227.
2. Paola Rogliani, Luigino Calzetta, Josuel Ora, Mario Cazzola & Mariaabriella Matera. Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis. BMC. Multidisciplinary Respiratory Medicine. August 2019. [Accessed on 15th November 2022]. https://mrmjournal.biomedcentral.com/articles/10.1186/s40248-019-0189-0
3. A.B.C Farmaceutici S.P.A. Doxofylline. [Revised in March 2011] [Accessed on 15th November 2022]. https://www.abcfarmaceutici.it/uploads/news/40_file3_en.pdf
4. Central Drugs Standard Control Organization (CDSCO). Doxofylline MR Tablet 650mg. Doxofylline Tablet (400mg) and Doxofylline tablets & Syrup. [Accessed on 15th November 2022]. https://cdscoonline.gov.in/CDSCO/Drugs
PRODUCT DETAILS
Country Of Origin
India
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