DIOCOLD AF Syrup 60ml

US$16.00US$22.00 (-27%)

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INTRODUCTION

DIOCOLD AF SYRUP is a combination of Phenylephrine and Chlorpheniramine which belongs to the group of medicines called Nasal decongestants and Antihistamines respectively. It is used to relieve nasal and sinus congestion, allergic symptoms of the nose or throat due to upper respiratory tract allergies, sinus pain and headache.

Also, it is used adjunctly with antibacterials to treat sinusitis (inflammation of the tissue lining the sinuses), tonsillitis (inflammation of the tonsils) and otitis media (middle ear infection).

Before giving DIOCOLD AF SYRUP to your child, inform child’s doctor if your child has kidney, liver or heart problems, diabetes, fits or severely raised blood pressure.

DIOCOLD AF SYRUP is not recommended for use in pregnant or breast-feeding women and elderly patients as it is used only in children.

The most common side effects of DIOCOLD AF SYRUP are nausea, vomiting, dry mouth, dizziness and tiredness. Consult your child’s doctor if any of the side effects worsen.

USES OF DIOCOLD AF SYRUP
Relieves nasal and sinus congestion
Relieves allergic symptoms of the nose or throat due to upper respiratory tract allergies
Relieves sinus pain and headache
Used adjunctly with antibacterials to treat sinusitis, tonsillitis and otitis media
HOW DIOCOLD AF SYRUP WORKS

DIOCOLD AF SYRUP relieves cold symptoms where phenylephrine decreases nasal congestion by acting on α1-adrenergic receptors in the small vessels of the nasal mucosa to produce constriction, resulting in decreased swelling and increased drainage of the sinus cavities and chlorpheniramine binds to the histamine H1 receptor and blocks its action, resulting in temporary relief of the negative symptoms (runny nose, sneezing, watery and itchy eyes) brought on by histamine.

DIRECTIONS FOR USE

Give DIOCOLD AF SYRUP to your child as advised by the physician. Shake well before use. Use a measuring cup to properly measure the dose. Your child’s doctor will decide the correct dose and duration of DIOCOLD AF SYRUP for your child depending upon child’s age, body weight and disease condition.

SIDE EFFECTS OF DIOCOLD AF SYRUP
COMMON
Drowsiness and sedation
Disturbance in concentrating, un-coordination, dizziness, headache
Blurred vision
Nausea or vomiting
Dry mouth
Tiredness
RARE
Increased heart rate, palpitation
Fear, anxiety, restlessness
Tremor, weakness
Painful urination
Insomnia
Hallucinations, convulsions

Stop giving DIOCOLD AF SYRUP to your child and contact doctor immediately if your child experiences any of the following side effects:

Develop rash, hives, itching, red or swollen or blistered or peeling skin; wheezing, tightness in the chest or throat, trouble breathing, swallowing or talking, unusual hoarseness or swelling of the mouth, face lips, tongue or throat
HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your child’s head. Advise your child to take rest in a quiet room. Massage child’s scalp or head with mild pressure for relieving effect. Consult child’s doctor if the symptom does not improve.

Nausea and vomiting:

Follow simple meal plan for your child while administering DIOCOLD AF SYRUP. Avoid giving foods that are oily, fried or spicy foods. Do not let your child to lie down or sleep immediately after eating. Consult child’s doctor if the symptom does not improve.

Dry mouth:

Tell your child to sip water regularly and other sugar free liquids. Tell your child not to use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Consult child’s doctor if the symptom does not improve.

WARNING & PRECAUTIONS
PREGNANCY

DIOCOLD AF SYRUP is not recommended for use in pregnant women as it is used only in children. Consult your doctor for advice.

BREASTFEEDING

DIOCOLD AF SYRUP is not recommended for use in breast-feeding women as it is used only in children. Consult your doctor for advice.

DRIVING AND USING MACHINES

Do not let your child ride bicycles or drive other vehicles or operate any tools if your child experiences dizziness, drowsiness and sedation after taking DIOCOLD AF SYRUP.

ALCOHOL

Avoid medicines containing alcohol during administration of DIOCOLD AF SYRUP.

KIDNEY

DIOCOLD AF SYRUP should be used with caution in children with kidney failure. Consult your child’s doctor for advice before administration of DIOCOLD AF SYRUP to your child.

LIVER

DIOCOLD AF SYRUP should be used with caution in children with liver impairment. Consult your child’s doctor for advice before administration of DIOCOLD AF SYRUP to your child.

ALLERGY

Talk to your child’s doctor if your child is allergic to Phenylephrine, Chlorpheniramine or any other ingredients of this medicine.

HEART DISEASE

DIOCOLD AF SYRUP is not recommended for use in children with severely high blood pressure. DIOCOLD AF SYRUP should be used with caution in patients with any other cardiovascular problems. Consult your child’s doctor for advice before administration of DIOCOLD AF SYRUP to your child.

OTHERS

DIOCOLD AF SYRUP is not recommended for use if your child:

Has phaeochromocytoma (rare tumours that start in the inner part of the adrenal gland)
Peripheral or mesenteric vascular thrombosis (blood clots usually in legs or major veins (one or more) that drain blood from the intestine

Before giving DIOCOLD AF SYRUP to your child, inform your physician if your child:

Has diabetes
Has overactive thyroid
Has closed angle glaucoma
Has history of fits

Use in pediatrics:

DIOCOLD AF SYRUP should be used with caution in children from 1 month to 12 years of age. Consult your child’s doctor for advice before administration of DIOCOLD AF SYRUP.

Use in geriatrics:

DIOCOLD AF SYRUP is not recommended for use in elderly patients as it is used only in children. Consult your doctor for advice.

INTERACTIONS

A. Drug – Drug interactions:

Before giving DIOCOLD AF SYRUP to your child, inform to child’s doctor if your child is taking or receiving any of the following medicines: 

Medicines used to treat depression (Ex. selegiline, phenelzine, amitriptyline)
Ephedrine (used to treat low blood pressure)
Phenytoin (used to treat epilepsy)
Digoxin (used to treat irregular heartbeat)
Medicines used to treat anxiety and induce sleep (Ex. alprazolam, chlordiazepoxide, clonazepam)

Overdosage:

If you or anyone else accidentally take too much of DIOCOLD AF SYRUP, contact your doctor immediately or visit a nearby hospital. Overdosage symptoms of DIOCOLD AF SYRUP includes extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations and possibly seizures.

SYNOPSIS
Drug :   Phenylephrine, Chlorpheniramine
Pharmacological Category :   Nasal decongestant, Antihistamine
Therapeutic Indication :   Relieves nasal and sinus congestion, allergic symptoms, sinus pain, sinusitis, tonsillitis and otitis media (in addition with antibiotics)
Dosage Forms :   Capsule, Tablet, Syrup, Oral drops
MORE INFORMATION
Keep DIOCOLD AF SYRUP out of reach of children
Store at room temperature
FAQs ABOUT DIOCOLD AF SYRUP

What if I forget to give a dose of DIOCOLD AF SYRUP to my child?

If you forget to give a dose of DIOCOLD AF SYRUP to your child, give it as soon as you remember. However, omit the missed dose if it is almost time for the next one. Do not give the medicine two times to make up for the forgotten dose.

Can I stop giving DIOCOLD AF SYRUP to my child if the symptoms subside?

Continue giving DIOCOLD AF SYRUP to your child until your child’s doctor tells you to stop, unless your experience child’s any unwanted effects, worsening of the condition or any new symptoms. In such cases, contact your child’s doctor right away.

What precautions do I need to follow while giving DIOCOLD AF SYRUP to my child?

Before giving DIOCOLD AF SYRUP to your child, you must inform child’s doctor about their pre-existing conditions like any kidney, liver, heart or thyroid problems, diabetes, fits or severely raised blood pressure and any other allergies. Consult your child’s doctor if your child experiences anything different.

Can I give other medicines to my child along with DIOCOLD AF SYRUP?

Before giving DIOCOLD AF SYRUP to your child, inform your child’s doctor if your child is taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicines, as these might interact with each other and cause serious side effects.

Can DIOCOLD AF SYRUP be used in children with liver problems?

DIOCOLD AF SYRUP should be used with caution in children with liver impairment. Child’s doctor may monitor your child’s liver function before and during treatment with this medicine to prevent the risk of any unusual effects. Consult your child’s doctor for advice before administration of DIOCOLD AF SYRUP to your child.

REFERENCES

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Allergic Rhinitis. Pharmacotherapy Handbook. Ninth edition. Page- 813.

2. KD. Tripathi. Adrenergic System and Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 135.

3. Mayuresh Kiran and Lalit Pawaskar. Study of Safety and Efficacy for the Combination of Chlorpheniramine maleate and Phenylephrine in Infants suffering from Allergic Rhinitis and Associated Symptoms. International Research of Contemporary Medical Research. March 2019. [Accessed on 20th July 2022] https://www.ijcmr.com/uploads/7/7/4/6/77464738/ijcmr_2406_v1.pdf

4. PubChem Compound Summary for CID 2725, Chlorpheniramine. National Center for Biotechnology Information. June 2022. [Accessed on 20th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Chlorpheniramine#section=Mechanism-of-Action

5. Centaur Pharmaceuticals Pvt. Ltd. and Lab Daffodil. Sinarest AF Drops (Phenylephrine + Chlorpheniramine). [Revised in January 2022] [Accessed on 20th July 2022] https://www.centaurpharma.com/downloads/2022/pediatrics/cold/Sinarest%20AF%20oral%20drops.pdf

6. Centaur Pharmaceuticals Pvt. Ltd. and Lab Daffodil. Sinarest AF Drops/Syrups [Accessed on 20th July 2022] https://www.centaurpharma.com/downloads/Sinarest-AF-Syr-Drops2018.pdf

7. Zuventus Healthcare Limited. Maxtra Syrup (Phenylephrine + Chlorpheniramine maleate). [Accessed on 20th July 2022] http://www.zuventus.co.in/doctor_wise_products_selected.aspx?Medi_Id=149

8. GlaxoSmithKline Consumer Healthcare. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 20th July 2022] https://www.medicines.org.uk/emc/files/pil.3928.pdf

USEFUL DIAGNOSTIC TESTS
Nasal cytology
PRODUCT DETAILS
Country Of Origin
India

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DIOCOLD AF Syrup 60ml

US$16.00US$22.00 (-27%)

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