INTRODUCTION
ABETANATE S OINTMENT is a combination of Clobetasol propionate and Salicylic acid which belongs to a group of medicines called Topical Corticosteroids and Keratolytic agents, respectively. ABETANATE S OINTMENT is used to treat and provide relief from inflammatory manifestations of skin conditions such as psoriasis (skin condition marked by rash and itchiness) and eczema (skin inflammation) in affected individuals.
ABETANATE S OINTMENT is also used to provide relief from skin redness, itching and/or swelling due to various skin conditions. It is also indicated for use to treat other skin conditions such as dermatoses (skin lesion), seborrheic dermatitis of scalp (skin condition marked by scaly patches and red skin on the scalp) and/or ichthyosis vulgaris (inherited skin condition marked by dry & scaly skin) in affected individuals.
ABETANATE S OINTMENT is generally not recommended for use in patients allergic to clobetasol and/or salicylic acid. ABETANATE S OINTMENT is advised to be used in pregnant and breastfeeding women only if it is clearly necessary.
ABETANATE S OINTMENT is not recommended for use in children and adolescents (aged below 12 years). The medicine is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.
The most common side-effects associated with the use of ABETANATE S OINTMENT are irritation, burning, redness and/or stinging sensation (at the site of application), skin rash, itching and/or peeling/ thinning of skin. Consult your doctor if any of these symptoms worsens.
USES OF ABETANATE S OINTMENT
Treats and provide relief from inflammatory manifestations of skin conditions such as psoriasis and eczema
Provides relief from skin redness, itching and/or swelling due to various skin conditions
Treats other skin conditions such as dermatoses, seborrheic dermatitis of scalp and/or ichthyosis vulgaris in affected individuals
HOW ABETANATE S OINTMENT WORKS
ABETANATE S OINTMENT provides relief from psoriasis and eczema, where Clobetasol propionate prevents inflammation by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and/or itchy and Salicylic acid softens the skin by removing dead skin cells and breaking down keratin clumps which results in reducing itchiness and redness of skin, thus providing relief from psoriasis and eczema in affected individuals.
DIRECTIONS FOR USE
Always apply ABETANATE S OINTMENT as directed by your physician. It is for external use only. Wash your hands and apply a thin layer of medicine on the affected area. Avoid covering the affected area with airtight dressings unless recommended. Avoid applying the medicine on face, groin or axillae. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF ABETANATE S OINTMENT
COMMON
Irritation, burning, redness and/or stinging sensation at the site of application
Skin rash, itching
Peeling/thinning of skin
UNCOMMON
Erythema (skin redness)
Telangiectasia (condition marked by small, widened blood vessels on the skin)
RARE
Stop applying ABETANATE S OINTMENT and contact your doctor immediately if you experience any of the following side effects:
Blurred vision, dizziness, fainting and/or irregular heartbeat
Irritation and/or sensitization
HOW TO MANAGE SIDE EFFECTS
Itchy Skin:
Try to pat/tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants and/or moisturizers and use a skin softener regularly. Consult your doctor if the symptom does not improve or gets worse.
WARNING & PRECAUTIONS
PREGNANCY
ABETANATE S OINTMENT should be used with caution in pregnant women only if it is clearly necessary. Consult your doctor before applying it.
BREASTFEEDING
ABETANATE S OINTMENT should be used with caution in breastfeeding women only if it is clearly necessary. Consult your doctor before applying the medicine.
ALCOHOL
Inform your doctor if you are planning to consume alcohol while on treatment with ABETANATE S OINTMENT.
ALLERGY
Do not apply ABETANATE S OINTMENT if you are allergic to Clobetasol, salicylic acid and/or any other ingredients of this medicine.
OTHERS
Use in Paediatrics:
ABETANATE S OINTMENT is not recommended for use in children and adolescents (aged below 12 years). Consult your doctor before using the medicine.
Use in Geriatrics:
ABETANATE S OINTMENT should be used with caution in elderly patients (over 65 years of age) Consult your doctor before applying it.
INTERACTIONS
A. Drug – Drug interactions:
Inform your doctor if you are taking any ayurvedic, homeopathic and/or any other medicines before applying ABETANATE S OINTMENT.
Overdosage:
If you or anyone else applies too much of ABETANATE S OINTMENT or accidentally swallows it, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
SYNOPSIS
Drug : Clobetasol propionate, Salicylic acid
Pharmacological Category : Topical Corticosteroids, Keratolytic agent
Therapeutic Indication : Psoriasis, Eczema, Other skin conditions (such as dermatoses, seborrheic dermatitis of scalp and/or ichthyosis vulgaris
Dosage Forms : Cream, Lotion, Ointment
MORE INFORMATION
Keep ABETANATE S OINTMENT out of reach of children
Store ABETANATE S OINTMENT below 30°C
FAQs ABOUT ABETANATE S OINTMENT
What is ABETANATE S OINTMENT used for?
ABETANATE S OINTMENT is used to treat and provide relief from inflammatory manifestations of skin conditions such as psoriasis (skin condition marked by rash and itchiness) and eczema (skin inflammation). It is also used to provide relief from skin redness, itching and/or swelling (due to various skin conditions) which is also indicated for use to treat other skin conditions such as dermatoses (skin lesion), seborrheic dermatitis of scalp (skin condition marked by scaly patches and red skin on the scalp) and/or ichthyosis vulgaris (inherited skin condition marked by dry & scaly skin) in affected individuals.
What are the side effects of ABETANATE S OINTMENT?
The most common side-effects associated with the use of ABETANATE S OINTMENT are irritation, burning, redness and/or stinging sensation (at the site of application), skin rash, itching and/or peeling/ thinning of skin. Consult your doctor if any of these symptoms worsens.
How ABETANATE S OINTMENT works?
ABETANATE S OINTMENT provides relief from psoriasis and eczema, where Clobetasol propionate prevents inflammation by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and/or itchy and Salicylic acid softens the skin by removing dead skin cells and breaking down keratin clumps which results in reducing itchiness and redness of skin, thus providing relief from psoriasis and eczema in affected individuals.
How ABETANATE S OINTMENT is applied?
Always apply ABETANATE S OINTMENT as directed by your physician. It is for external use only. Wash your hands and apply a thin layer of medicine on the affected area. Avoid covering the affected area with airtight dressings unless recommended. Avoid applying the medicine on face, groin or axillae. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Can ABETANATE S OINTMENT be used in pregnant and breastfeeding women?
Yes, ABETANATE S OINTMENT can be used but with caution in pregnant and breastfeeding women only if it is clearly necessary. Consult your doctor before applying ABETANATE S OINTMENT.
REFERENCES
1. KD. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 889, 889.
2. Jana Petersen, Claudia Garbe, Sandra Wolf, Brigitte Stephan, Matthias Augustin, Kristina Hagenström. Medicinal Treatment of Elderly Psoriasis Patients before and after Entering a Nursing Home. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in September 2022] [Accessed on 16th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498407/
3. Lilit Garibyan, Albert S. Chiou, Sarina B. Elmariah. Advanced Aging Skin and Itch: Addressing an Unmet Need. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in June 2014] [Accessed on 16th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051285/
4. Ziska Pharmaceuticals Ltd. Closalic Ointment. [Accessed on 16th November 2022] http://ziskapharma.com/uploads/products/Closalic_Insert_Size.pdf
5. Sangrose Laboratories Pvt. Ltd. Closal. [Accessed on 16th November 2022] https://sangroselaboratories.com/products/
6. Swisschem Dermacare. CLOBSOL-S. [Accessed on 16th November 2022] https://www.swisscosmed.in/product/clobetasol-salicylic-acid-3
7. Care Formulation Labs Pvt. Ltd. MYSELIC. [Accessed on 16th November 2022] https://careformulationlabs.com/product/myselic/
8. Velite. CLOBISOL-S LOTION. [Accessed on 16th November 2022] https://velite.in/index.php?route=product/product&product_id=183
9. Ederma Pharma India Pvt Ltd. ECZIVATE-S 6% LOTION. [Accessed on 16th November 2022] https://edermapharma.com/product/eczivate-s-6-lotion/
10. QndQ Derma. Comply-S. [Accessed on 16th November 2022] https://www.qndqdermacare.com/product/comply-s
11. Hanuchem Laboratories. Comply-S. [Accessed on 16th November 2022] https://www.hanuchemlabs.com/ointemnts
12. Innovative Pharmaceuticals Pvt Ltd. Clotrol-S Ointment. [Accessed on 16th November 2022] https://www.innovativepharma.in/product/clotrol-s-ointment/
USEFUL DIAGNOSTIC TESTS
Patch test
Skin biopsy
Country Of Origin
India
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